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Machine translation
1. (WO2004026266) SYNTHESIS AND APPLICATIONS OF TRINUCLEOTIDE pCpCpA-3′-NH-AMINOACYL DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/026266    International Application No.:    PCT/US2003/030312
Publication Date: 01.04.2004 International Filing Date: 18.09.2003
IPC:
C07H 21/04 (2006.01)
Applicants: UNIVERSITY OF MASSACHUSETTS [US/US]; One Beacon Street, 26th Floor, Boston, MA 02108 (US) (For All Designated States Except US).
ZHANG, Biliang [US/US]; (US) (For US Only)
Inventors: ZHANG, Biliang; (US)
Agent: FASSE, Peter, J.; Fish & Richardson P.C., 225 Franklin Street, Boston, MA 02110-2804 (US)
Priority Data:
60/411,649 18.09.2002 US
Title (EN) SYNTHESIS AND APPLICATIONS OF TRINUCLEOTIDE pCpCpA-3′-NH-AMINOACYL DERIVATIVES
(FR) SYNTHESE ET APPLICATIONS DE DERIVES DE PCPCPA-3'-NH-AMINOACYLE TRINUCLEOTIDIQUES
Abstract: front page image
(EN)The present invention relates to the synthesis of novel compounds for the inhibition of peptide synthesis in the ribosome. It also relates to improved methods for directly monitoring peptide bond formation in the ribosome. These compounds can be used for high throughput screening of proposed therapeutically active drug species (e.g., antibiotics) targeted to ribosomes.
(FR)La présente invention concerne la synthèse de nouveaux composés qui servent à inhiber la synthèse peptidique dans le ribosome. L'invention a également pour objet des procédés améliorés pour surveiller directement la formation de liaisons peptidiques dans le ribosome. Ces composés peuvent être utilisés pour le criblage à rendement élevé d'espèces de substances à action thérapeutiques proposées (par exemple d'antibiotiques) qui ciblent les ribosomes.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)