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Machine translation
1. (WO2004026251) PROCESS FOR DECREASING AGGREGATE LEVELS OF PEGYLATED PROTEIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/026251    International Application No.:    PCT/US2003/029546
Publication Date: 01.04.2004 International Filing Date: 22.09.2003
Chapter 2 Demand Filed:    15.12.2003    
IPC:
C07K 1/18 (2006.01), C07K 14/61 (2006.01)
Applicants: PHARMACIA CORPORATION [US/US]; Global Patent Department, P.O. Box 1027, St. Louis, MO 63006 (US) (For All Designated States Except US).
BOYLE, Denis, M. [US/US]; (US) (For US Only).
BUCKLEY, John, J. [US/US]; (US) (For US Only).
JOHNSON, Gary, V. [US/US]; (US) (For US Only).
STEINMEYER, David, E. [US/US]; (US) (For US Only).
TOAL, Michele [US/US]; (US) (For US Only).
AYKENT, Serdar [US/US]; (US) (For US Only).
RATHORE, Anurag, S. [IN/US]; (US) (For US Only)
Inventors: BOYLE, Denis, M.; (US).
BUCKLEY, John, J.; (US).
JOHNSON, Gary, V.; (US).
STEINMEYER, David, E.; (US).
TOAL, Michele; (US).
AYKENT, Serdar; (US).
RATHORE, Anurag, S.; (US)
Agent: PATHAK, Ajay, S.; Banner & Witcoff, Ltd., 11th Floor, 1001 G Street, N.W., Washington, DC 20001-4597 (US)
Priority Data:
60/412,227 20.09.2002 US
10/646,798 25.08.2003 US
10/662,884 16.09.2003 US
Title (EN) PROCESS FOR DECREASING AGGREGATE LEVELS OF PEGYLATED PROTEIN
(FR) PROCEDE SERVANT A DIMINUER LA TOTALITE DES NIVEAUX D'UNE PROTEINE PEGYLEE
Abstract: front page image
(EN)The present invention is directed generally to recombinant methods for making a desired pegylated protein and pooling of same. These method(s) yield a polypeptide product containing reduced levels of aggregate thereof pooled to provide the desired pegylated isoforms thereof.
(FR)L'invention concerne, de façon générale, des procédés de recombinaison servant à produire une protéine PEGylée et à en effectuer le regroupement. Ces procédés permettent d'obtenir un polypeptide contenant des niveaux limités d'agrégat de ladite protéine regroupés de manière à produire les isoformes PEGylées de ladite protéine.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)