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1. (WO2004026250) RE-ACTIVATED T-CELLS FOR ADOPTIVE IMMUNOTHERAPY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/026250    International Application No.:    PCT/US2003/029539
Publication Date: 01.04.2004 International Filing Date: 17.09.2003
IPC:
A61K 39/395 (2006.01), C07K 16/28 (2006.01), C12N 5/02 (2006.01), C12N 5/0783 (2010.01)
Applicants: VALEOCYTE THERAPIES LLC [US/US]; P.O. Box 26670, San Diego, CA 92196 (US)
Inventors: GRUENBERG, Micheal, L.; (US).
CHAVAN, Surendra; (US)
Agent: HILL, Laurie, L.; Morrison & Foerster LLP, 3811 Valley Centre Drive, Suite 500, San Diego, CA 92130-2332 (US)
Priority Data:
10/246,647 17.09.2002 US
Title (EN) RE-ACTIVATED T-CELLS FOR ADOPTIVE IMMUNOTHERAPY
(FR) LYMPHOCYTES T RE-ACTIVES POUR UNE IMMUNOTHERAPIE ADOPTIVE
Abstract: front page image
(EN)A method for increasing the cytokine production of T-cells intended for use in adoptive immunotherapy is provided. The method improves adoptive immunotherapy methods where the efficacy of the treatment is dependent, at least in part, on the amount of cytokine production from the cells. In practicing the method, ex-vivo produced T-cells intended for use in adoptive immunotherapy treatment protocols are allowed to rest after harvest and then are re-activated just prior to infusion.
(FR)L'invention concerne une méthode d'augmentation de la production de cytokine de lymphocytes T destinée à l'immunothérapie adoptive. Cette méthode permet d'améliorer des méthodes d'immunothérapie adoptive, dans lesquelles l'efficacité du traitement dépend, au moins en partie, de la quantité de la production de cytokine provenant des cellules. La réalisation de cette méthode permet à des lymphocytes T produits ex vivo utilisés dans des protocoles de traitement d'immunothérapie adoptive de se reposer après la récolte et, puis, d'être réactivés juste avant une perfusion.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)