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1. WO2004019993 - SELF-IMMOLATIVE DENDRIMERS RELEASING MANY ACTIVE MOIETIES UPON A SINGLE ACTIVATING EVENT

Publication Number WO/2004/019993
Publication Date 11.03.2004
International Application No. PCT/IL2003/000711
International Filing Date 28.08.2003
IPC
A61K 47/48 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
48the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
CPC
A61K 47/6949
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
69the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
6949inclusion complexes, e.g. clathrates, cavitates or fullerenes
B82Y 5/00
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
5Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
C08G 83/003
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
83Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
002Dendritic macromolecules
003Dendrimers
Applicants
  • RAMOT AT TEL AVIV UNIVERSITY LTD. [IL]/[IL] (AllExceptUS)
  • THE SCRIPPS RESEARCH INSTITUTE [US]/[US] (AllExceptUS)
  • SHABAT, Doron [IL]/[IL] (UsOnly)
  • LIST, Benjamin [US]/[DE] (UsOnly)
  • AMIR, Roey, Jacob [IL]/[IL] (UsOnly)
  • SHAMIS, Marina [IL]/[IL] (UsOnly)
  • PESSAH, Neta [IL]/[IL] (UsOnly)
Inventors
  • SHABAT, Doron
  • LIST, Benjamin
  • AMIR, Roey, Jacob
  • SHAMIS, Marina
  • PESSAH, Neta
Agents
  • G. E. EHRLICH (1995) LTD.
Priority Data
60/406,95830.08.2002US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SELF-IMMOLATIVE DENDRIMERS RELEASING MANY ACTIVE MOIETIES UPON A SINGLE ACTIVATING EVENT
(FR) DENDRIMERES AUTO-IMMOLATEURS LIBERANT PLUSIEURS FRAGMENTS ACTIFS LORS D'UN SEUL EVENEMENT ACTIVATEUR
Abstract
(EN)
A self-immolative dendrimer capable of releasing all of its tail units upon a single cleavage event, methods of synthesizing same and uses thereof are disclosed.
(FR)
L'invention concerne un dendrimère auto-immolateur pouvant libérer toutes ses unités de queue lors d'un seul événement de clivage. L'invention concerne également des procédés de synthèse et d'utilisation de ce dendrimère.
Also published as
Latest bibliographic data on file with the International Bureau