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1. (WO2004019886) METHODS FOR UP-REGULATING ANTIGEN EXPRESSION IN TUMORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2004/019886 International Application No.: PCT/US2003/027125
Publication Date: 11.03.2004 International Filing Date: 29.08.2003
IPC:
A61B 19/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
19
Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B1/-A61B18/149
Applicants:
CYTOCURE LLC [US/US]; 149 Laurel Drive Needham, MA 02492-3206, US (AllExceptUS)
DURDA, Paul, J. [US/US]; US (UsOnly)
KURNICK, James, T. [US/US]; US (UsOnly)
DUNN, Ian, S. [AU/AU]; AU (UsOnly)
Inventors:
DURDA, Paul, J.; US
KURNICK, James, T.; US
DUNN, Ian, S.; AU
Agent:
BEDGOOD, Robert, M.; Pillsbury Winthrop LLP 11682 El Camino Real, Suite 200 Carmel Valley, CA 92130-1593, US
Priority Data:
60/407,49229.08.2002US
Title (EN) METHODS FOR UP-REGULATING ANTIGEN EXPRESSION IN TUMORS
(FR) PROCEDES DE REGULATION POSITIVE DE L'EXPRESSION ANTIGENIQUE DANS DES TUMEURS
Abstract:
(EN) The invention provides methods of modulating tumor antigen associated (TAA) expression, and methods of modulating TAA expression in order to treat a tumor. More particularly, the invention provides methods of increasing an immune response against tumor cell. Methods include administering to a subject with a tumor an amount of IFN-&bgr; receptor agonist and tumor associated antigen (TAA) sufficient to increase an immune response against the tumor cell.
(FR) L'invention concerne des procédé de modulation de l'expression d'antigène associé à une tumeur (TAA), et des procédés de modulation de l'expression TAA de façon à traiter une tumeur. Elle concerne, plus particulièrement, des procédés permettant d'augmenter une réponse immune contre une cellule tumorale. Ces procédés consistent à administrer à un sujet atteint d'une tumeur une quantité suffisante d'un agoniste de récepteur d'IFN-$g(b) et d'un antigène associé à la tumeur (TAA) afin d'augmenter la réponse immune contre la cellule tumorale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NZ538688EP1542609ES2399749CA2497151AU2003268275