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1. WO2004018658 - HUMAN BONE STEM CELLS

Publication Number WO/2004/018658
Publication Date 04.03.2004
International Application No. PCT/JP2003/010554
International Filing Date 21.08.2003
IPC
C12N 5/077 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
077Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
A61K 35/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
CPC
A61K 35/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
A61P 19/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
C12N 5/0605
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
06Animal cells or tissues; Human cells or tissues
0602Vertebrate cells
0603Embryonic cells
0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
C12N 5/0668
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
06Animal cells or tissues; Human cells or tissues
0602Vertebrate cells
0652Cells of skeletal and connective tissues; Mesenchyme
0662Stem cells
0668Mesenchymal stem cells from other natural sources
Applicants
  • SRL, INC. [JP]/[JP] (AllExceptUS)
  • SAKURAGAWA, Norio [JP]/[JP]
  • UCHIDA, Saiko [JP]/[JP]
Inventors
  • SAKURAGAWA, Norio
  • UCHIDA, Saiko
Agents
  • TANIGAWA, Hidejiro
Priority Data
2002-24428023.08.2002JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) HUMAN BONE STEM CELLS
(FR) CELLULES SOUCHES D'OS HUMAINS
(JA) ヒト骨幹細胞
Abstract
(EN)
Bone stem cells which can be stably supplied without any problem of compatibility in transplantation. These bone stem cells, which are separated from human amniotic mesenchymal cell layer, are usable in osteogenesis in a bone-lacking site and the like.
(FR)
Cette invention se rapporte à des cellules souches d'os qui peuvent être fournies de façon stable sans problème de compatibilité au moment d'une transplantation. Ces cellules souches d'os, qui sont séparées de la couche des cellules mésenchymateuses amniotiques humaines, sont utiles en ostéogenèse en cas de manque osseux et similaire.
(JA)
安定供給が可能であり、移植の際の適合性が問題にならない骨幹細胞が開示されている。本発明の骨幹細胞は、ヒト羊膜間葉細胞層から分離される。この骨肝細胞は、骨欠損部等における骨形成に用いることができる。
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