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1. WO2004017991 - USE OF IAP FOR THE DIAGNOSIS AND OF IAP-INHIBITORS FOR THE TREATMENT OF HODGKIN’S LYMPHOMAS

Publication Number WO/2004/017991
Publication Date 04.03.2004
International Application No. PCT/EP2003/007889
International Filing Date 18.07.2003
IPC
C07K 16/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61P 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
C07K 14/4747
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
4701not used
4747Apoptosis related proteins
C07K 16/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
Applicants
  • CELL CENTER COLOGNE GMBH [DE]/[DE] (AllExceptUS)
  • KRÖNKE, Martin [DE]/[DE] (UsOnly)
  • KASHKAR, Hamid [IR]/[DE] (UsOnly)
  • HAMILTON-DUTOIT, Stephen Jaques [GB]/[DK] (UsOnly)
  • JÜRGENSMEIER, Juliane, M. [DE]/[GB] (UsOnly)
Inventors
  • KRÖNKE, Martin
  • KASHKAR, Hamid
  • HAMILTON-DUTOIT, Stephen Jaques
  • JÜRGENSMEIER, Juliane, M.
Agents
  • STEINECKE, Peter
Priority Data
102 37 139.313.08.2002DE
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF IAP FOR THE DIAGNOSIS AND OF IAP-INHIBITORS FOR THE TREATMENT OF HODGKIN’S LYMPHOMAS
(FR) UTILISATION DES IAP POUR LE DIAGNOSTIC ET DES INHIBITEURS D'IAP POUR LE TRAITEMENT DE LA MALADIE DE HODGKIN
Abstract
(EN)
A novel use of inhibitors of IAPs (inhibitors of apoptosis) in compositions for the treatment of Hodgkin’s lymphomas is described. In particular, XIAP-inhibitors are disclosed for methods of treatment of Hodgkin’s lymphomas. Furthermore, diagnostic methods for the detection of Hodgkin’s lymphomas using IAP specific agents are provided.
(FR)
Cette invention se rapporte à une nouvelle utilisation d'inhibiteurs d'IAP (inhibiteurs de l'apoptose) dans des compositions servant au traitement de la maladie de Hodgkin. Cette invention concerne en particulier des inhibiteurs de XIAP utilisés dans des procédés de traitement de la maladie de Hodgkin. Cette invention concerne en outre des procédés diagnostiques permettant la détection de la maladie de Hodgkin au moyen d'agents spécifiques à base d'IAP.
Also published as
Latest bibliographic data on file with the International Bureau