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Machine translation
1. (WO2004010108) METHOD FOR THE IDENTIFICATION OF LIGANDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/010108    International Application No.:    PCT/US2003/023247
Publication Date: 29.01.2004 International Filing Date: 23.07.2003
Chapter 2 Demand Filed:    10.02.2004    
IPC:
G01N 33/53 (2006.01), G01N 33/567 (2006.01)
Applicants: 3-DIMENSIONAL PHARMACEUTICALS, INC. [US/US]; Eagleview Corporate Center, 665 Stockton Drive, Suite 104, Exton, PA 19341 (US) (For All Designated States Except US).
BONE, Roger, F. [US/US]; (US) (For US Only).
RENTZEPERIS, Dionisios [US/US]; (US) (For US Only).
ASKARI, Hossein [US/IR]; (US) (For US Only).
SPRINGER, Barry, A. [US/US]; (US) (For US Only)
Inventors: BONE, Roger, F.; (US).
RENTZEPERIS, Dionisios; (US).
ASKARI, Hossein; (US).
SPRINGER, Barry, A.; (US)
Agent: NORTON, Vicki, G.; Pillsbury Winthrop LLP, 11682 El Camino Real, Suite 200, San Diego, CA 92130-2092 (US)
Priority Data:
60/398,023 24.07.2002 US
60/413,843 27.09.2002 US
60/413,866 27.09.2002 US
Title (EN) METHOD FOR THE IDENTIFICATION OF LIGANDS
(FR) METHODE D'IDENTIFICATION DE LIGANDS
Abstract: front page image
(EN)The present invention relates generally to a method of identifying ligands that modulate protein-protein interactions. More particularly, the present invention relates to methods of determining agonists or antagonists of a co-regulator dependent target molecule based on the ability to modify the stability of the target molecule in a tissue­-selective manner.
(FR)La présente invention concerne généralement une méthode d'identification de ligands, qui module des interactions protéine-protéine. Plus particulièrement, l'invention concerne des méthodes pour déterminer des agonistes et des antagonistes d'une molécule cible dépendante d'un co-régulateur, ces méthodes étant basées sur l'aptitide à modifier la stabilité de la molécule cible d'une manière sélective pour le tissu.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)