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Machine translation
1. (WO2004009815) SILENCING HYBRID GENE EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/009815    International Application No.:    PCT/GB2003/003125
Publication Date: 29.01.2004 International Filing Date: 21.07.2003
Chapter 2 Demand Filed:    19.02.2004    
IPC:
A61K 38/00 (2006.01), C12N 15/11 (2006.01)
Applicants: MILNER, Anne, Josephine [GB/GB]; (GB)
Inventors: MILNER, Anne, Josephine; (GB)
Agent: HARRISON GODDARD FOOTE; Quality House, Quality Court, Chancery Lane, London WC2A 1HT (GB)
Priority Data:
0216929.0 20.07.2002 GB
Title (EN) SILENCING HYBRID GENE EXPRESSION
(FR) NEUTRALISATION DE L'EXPRESSION D'UN GENE CHIMERE
Abstract: front page image
(EN)The present invention provides a method of selectively silencing the expression of a hybrid gene formed from at least two gene elements. The method comprises introducing into a cell containing said hybrid gene an RNA construct comprising a nucleotide sequence which is homologous to mRNA which includes genetic information of the at least two gene elements. The present invention also provides an RNA construct with a nucleotide sequence which is homologous to mRNA transcribed from a hybrid gene formed from at least two gene elements wherein said RNA construct comprises RNA which is homologous to at least two of said elements forming the hybrid gene.
(FR)La présente invention concerne une méthode qui permet de neutraliser sélectivement l'expression d'un gène chimère formé d'au moins deux éléments géniques. La méthode consiste à introduire dans une cellule contenant ledit gène chimère une construction d'ARN comprenant une séquence nucléotidique homologue de l'ARNm, lequel contient une information génétique de l'élément génique ou des deux éléments géniques. L'invention concerne en outre une construction d'ARN comprenant une séquence nucléotidique homologue d'un ARNm transcrit d'un gène chimère formé d'au moins deux éléments géniques, laquelle construction d'ARN comprend un ARN homologue d'au moins deux desdits éléments formant le gène chimère.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)