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Machine translation
1. (WO2004009783) TRUNCATED RGR IN T CELL MALIGNANCY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/009783    International Application No.:    PCT/US2003/022819
Publication Date: 29.01.2004 International Filing Date: 23.07.2003
IPC:
C07K 14/82 (2006.01)
Applicants: NEW YORK UNIVERSITY [US/US]; 70 Washington Square, New York, NY 10012 (US) (For All Designated States Except US).
PELLICER, Angel [ES/US]; (US) (For US Only).
LEONARDI, Peter [US/US]; (US) (For US Only).
INGHIRAMI, Giorgio [US/US]; (US) (For US Only)
Inventors: PELLICER, Angel; (US).
LEONARDI, Peter; (US).
INGHIRAMI, Giorgio; (US)
Agent: BROWDY AND NEIMARK, P.L.L.C.; 624 Ninth Street N.W., Suite 300, Washington, DC 20001-5303 (US)
Priority Data:
60/397,873 24.07.2002 US
Title (EN) TRUNCATED RGR IN T CELL MALIGNANCY
(FR) ONCOGENE RGR HUMAIN ET PRODUITS DE TRANSCRIPTION DE CELUI-CI DETECTES DANS LES AFFECTIONS MALIGNES LIEES AUX LYMPHOCYTES T, ANTICORPS DIRIGES CONTRE LES POLYLPEPTIDES CODES ET METHODES D'UTILISATION
Abstract: front page image
(EN)Naturally-occurring variants of human Rgr oncogene protein, in particular, abnormally truncated variants found in T cell malignancies, as well as the human Rgr protein are encompassed by the present invention. Also included are antibodies thereto and nucleic acid molecules encoding human Rgr protein and naturally-occurring variants thereof. The present invention further provides methods for diagnosing and treating T cell malignancies associated with abnormally truncated transcripts of human rgr oncogene and/or abnormal truncation of human Rgr protein.
(FR)L'invention concerne des variants naturels de la protéine oncogène Rgr humaine, en particulier des variants à troncature anormale qu'on trouve dans les affections malignes liées aux lymphocytes T, ainsi que la protéine Rgr humaine. L'invention concerne également les anticorps dirigés contre ceux-ci, ainsi que des molécules nucléotidiques codant pour la protéine Rgr humaine et les variants naturels de celle-ci. L'invention porte en outre sur des méthodes de diagnostic et de traitement des affections malignes liées aux lymphocytes T, qui sont associées à des produits de transcription présentant des troncatures anormales de l'oncogène Rgr humain et/ou à une troncature anormale de la protéine Rgr humaine.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)