Processing

Please wait...

Settings

Settings

Goto Application

1. WO2004009593 - PREPARATION OF 1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINES VIA1H-IMIDAZO [4,5-C]QUINOLIN-4-PHTHALIMIDE INTERMEDIATES

Publication Number WO/2004/009593
Publication Date 29.01.2004
International Application No. PCT/US2003/023153
International Filing Date 23.07.2003
Chapter 2 Demand Filed 12.02.2004
IPC
A61K 31/47 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
C07D 471/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
CPC
A61K 31/47
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • BIOGAL GYOGYSZERGYAR RT. [HU]/[HU] (AE, AG, AL, AM, AT, AU, AZ, BA, BE, BF, BG, BJ, BR, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NE, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW)
  • TEVA PHARMACEUTICALS USA, INC. [US]/[US] (BB)
  • MERLI, Valeriano [IT]/[IT] (UsOnly)
  • BIANCHI,Stefano [IT]/[IT] (UsOnly)
  • MANTOVANI, Silvia [IT]/[IT] (UsOnly)
Inventors
  • MERLI, Valeriano
  • BIANCHI,Stefano
  • MANTOVANI, Silvia
Agents
  • BRAINARD, Charles, R.
Priority Data
60/397,60723.07.2002US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PREPARATION OF 1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINES VIA1H-IMIDAZO [4,5-C]QUINOLIN-4-PHTHALIMIDE INTERMEDIATES
(FR) PREPARATION DE 1H-IMIDAZO[4,5-C]QUINOLINE-AMINES PAR LE BIAIS D'INTERMEDIAIRES DE 1H-[4,5-C]QUINOLOINE-4-PHTALIMIDE
Abstract
(EN)
The invention provides 1H-imidazo(4,5-C) quinolin-4-phthalimide intermediates useful in the synthesis of 1H-imidazo(4,5-C) quinoline-4-amines, particularly Imiquimod. The invention further provides a method for making the intermediates and a method for making 1H-imidazo (4,5-C) quinoline-4-amines via the intermediates.
(FR)
L'invention concerne des intermédiaires de 1H-imidazo(4,5-C)quinoline-4-phtalimide s'utilisant dans la synthèse de 1H-imidazo[4,5-C]quinoline-4-amines, notamment l'imiquimod. L'invention concerne en outre un procédé de production d'intermédiaires et un procédé de production de 1H-imidazo[4,5-c}]quinoline-4-amines par le biais des intermédiaires.
Other related publications
Latest bibliographic data on file with the International Bureau