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1. (WO2004009533) ACETYLAMINO BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/009533    International Application No.:    PCT/US2003/023183
Publication Date: 29.01.2004 International Filing Date: 23.07.2003
Chapter 2 Demand Filed:    19.02.2004    
IPC:
A61K 31/16 (2006.01), A61K 31/33 (2006.01), C07C 235/24 (2006.01), C07C 323/62 (2006.01), C07C 327/42 (2006.01), C07D 207/273 (2006.01), C07D 209/48 (2006.01), C07D 213/64 (2006.01), C07D 239/38 (2006.01), C07D 257/04 (2006.01), C07D 271/06 (2006.01), C07D 317/64 (2006.01), C07D 405/12 (2006.01)
Applicants: PTC THERAPEUTICS, INC. [US/US]; 100 Corporate Court, Middlesex Business Center, South Plainfield, NJ 07080 (US) (For All Designated States Except US).
TULARIK INC. [US/US]; 1120 Veterans Boulevard, South San Francisco, CA 94080 (US) (For All Designated States Except US).
WILDE, Richard, G. [US/US]; (US) (For US Only).
WELCH. Ellen, M. [US/US]; (US) (For US Only).
TAKASUGI, James, Jan [US/US]; (US) (For US Only).
ALMSTEAD, Neil, G. [US/US]; (US) (For US Only).
RUBENSTEIN, Steven, Marc [US/US]; (US) (For US Only).
BECKMANN, Holger [DE/DE]; (DE) (For US Only)
Inventors: WILDE, Richard, G.; (US).
WELCH. Ellen, M.; (US).
TAKASUGI, James, Jan; (US).
ALMSTEAD, Neil, G.; (US).
RUBENSTEIN, Steven, Marc; (US).
BECKMANN, Holger; (DE)
Agent: INSOGNA, Anthony, M.; Jones Day LLP, 222 EAst 41st Street, New York, NY 10017 (US)
Priority Data:
60/398,267 24.07.2002 US
Title (EN) ACETYLAMINO BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE
(FR) COMPOSES D'ACIDE ACETYLAMINO BENZOIQUE ET LEUR UTILISATION POUR LA SUPPRESSION DE NON-SENS ET LE TRAITEMENT DE MALADIE
Abstract: front page image
(EN)Novel acetylamino benzoic acid compounds, methods of using and pharmaceutical compositions comprising an acetylamino benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.
(FR)L'invention concerne de nouveaux composés d'acide acétyl amino benzoïque, des procédés d'utilisation d'un dérivé d'acide acétyl amino benzoïque et des compositions pharmaceutiques comprenant ce dernier. Il s'agit notamment de procédés de traitement ou de prévention d'une maladie qui sont améliorés par la modulation de la terminaison de translation prématurée ou la dégradation de l'ARNm médiée par les non-sens, ou qui améliorent au moins un symptôme qui y est associé.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)