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Machine translation
1. (WO2004009073) P-GLYCOPROTEIN INHIBITOR COMPRISING OCTILONIUM BROMIDE AS AN EFFECTIVE INGREDIENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/009073    International Application No.:    PCT/KR2003/001441
Publication Date: 29.01.2004 International Filing Date: 21.07.2003
Chapter 2 Demand Filed:    19.02.2004    
IPC:
A61K 9/50 (2006.01), A61K 31/245 (2006.01), A61K 45/06 (2006.01)
Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY [KR/KR]; 39-1, Hawolgok-Dong, Sungbook-Gu, Seoul 136-791 (KR) (For All Designated States Except US).
CHUNG, Hesson [KR/KR]; (KR) (For US Only).
JEONG, Seo-Young [KR/KR]; (KR) (For US Only).
KWON, Ick-Chan [KR/KR]; (KR) (For US Only).
PARK, Yeong-Taek [KR/KR]; (KR) (For US Only).
LEE, In-Hyun [KR/KR]; (KR) (For US Only).
YUK, Soon-Hong [KR/KR]; (KR) (For US Only)
Inventors: CHUNG, Hesson; (KR).
JEONG, Seo-Young; (KR).
KWON, Ick-Chan; (KR).
PARK, Yeong-Taek; (KR).
LEE, In-Hyun; (KR).
YUK, Soon-Hong; (KR)
Agent: PARK, Jang-Won; Jewoo Building 5th Floor, 200, Nonhyun-Dong, Gangnam-Gu, Seoul 135-010 (KR)
Priority Data:
10-2002-0042794 20.07.2002 KR
Title (EN) P-GLYCOPROTEIN INHIBITOR COMPRISING OCTILONIUM BROMIDE AS AN EFFECTIVE INGREDIENT
(FR) INHIBITEUR DE P-GLYCOPROTEINE CONTENANT DU BROMURE D'OCTYLONIUM COMME INGREDIENT ACTIF
Abstract: front page image
(EN)The present invention relates to a new use of octylonium bromide as p-glycoprotein inhibitor to increase cellular uptake of drugs. More particularly, the present invention provides octylonium bromide as a p-glycoprotein inhibitor to increase cellular uptake of drugs such as anticancer drugs by taking octylonium bromide simultaneously with or proceding drug administration.
(FR)L'invention concerne une nouvelle utilisation du bromure d'octylonium comme inhibiteur de la p-glycoprotéine afin d'augmenter l'apport cellulaire de médicaments. La présente invention concerne, plus particulièrement, l'utilisation du bromure d'octylonium comme inhibiteur de la p-glycoprotéine afin d'augmenter l'apport cellulaire de médicaments tels que les médicaments anticancéreux, par administration de bromure d'octylonium en même temps ou avant l'administration du médicament.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Korean (KO)