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1. (WO2004009072) TETRAPROPYLAMMONIUM TETRATHIOMOLYBDATE AND RELATED COMPOUNDS FOR ANTI-ANGIOGENIC THERAPIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/009072    International Application No.:    PCT/US2003/022914
Publication Date: 29.01.2004 International Filing Date: 23.07.2003
Chapter 2 Demand Filed:    11.02.2004    
IPC:
A61K 31/205 (2006.01), A61K 31/28 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN [US/US]; 3003 S. State Street, Suite 2701, Ann Arbor, MI 48109-1280 (US)
Inventors: BREWER, George, J.; (US).
MERAJVER, Sofia, D.; (US).
COUCOUVANIS, Dimitri; (US)
Agent: FUSSEY, Shelley, P., M.; Williams, Morgan & Amerson, P.C, 10333 Richmond Ave., Suite 1100, Houston, TX 77042 (US)
Priority Data:
60/397,804 23.07.2002 US
Title (EN) TETRAPROPYLAMMONIUM TETRATHIOMOLYBDATE AND RELATED COMPOUNDS FOR ANTI-ANGIOGENIC THERAPIES
(FR) TETRAPROPYLAMMONIUM TETRATHIOMOLYBDATE ET COMPOSES ASSOCIES POUR THERAPIES ANTI-ANGIOGENIQUES
Abstract: front page image
(EN)Disclosed are copper-binding compounds with improved properties and methods of using such compounds in the prevention and treatment of angiogenic diseases, such as cancer. Advantages of the invention include the enhanced stability of the compounds, which is achieved without reduction in efficacy. Pharmaceutical compositions, therapeutic kits and combination treatment methods and uses are also provided.
(FR)L'invention concerne des composés à liaison du cuivre présentant des propriétés améliorées, et des procédés consistant à utiliser ces composés pour prévenir et traiter des maladies angiogéniques, telles que le cancer. Les composés décrits dans cette invention présente une meilleure stabilité sans réduction de l'efficacité. La présente invention concerne également des compositions pharmaceutiques, des trousses thérapeutiques, des polythérapies, ainsi que des utilisations.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)