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1. (WO2004009065) HYPOGLYCEMIC AGENT, LIVER PROTECTING AGENT AND ANTICANCER AGENT CONTAINING LIGNANS ORIGINATING IN HONGDOUSHAN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/009065    International Application No.:    PCT/JP2003/009370
Publication Date: 29.01.2004 International Filing Date: 23.07.2003
Chapter 2 Demand Filed:    08.03.2004    
IPC:
A61K 31/085 (2006.01), A61K 31/341 (2006.01), C07D 307/12 (2006.01)
Applicants: KOTOSUGI INC. [JP/JP]; Mori Bldg., 5-3, Aihara, Sagamihara-shi, Kanagawa 229-1101 (JP) (For All Designated States Except US).
KADOTA, Shigetoshi [JP/JP]; (JP) (For US Only).
NOBUKAWA, Takahiro [JP/JP]; (JP) (For US Only)
Inventors: KADOTA, Shigetoshi; (JP).
NOBUKAWA, Takahiro; (JP)
Agent: FUJIWARA, Michihiko; 49-31, Uji-jadzuka, Uji-shi, Kyoto 611-0021 (JP)
Priority Data:
2002-214694 24.07.2002 JP
2003-119178 24.04.2003 JP
Title (EN) HYPOGLYCEMIC AGENT, LIVER PROTECTING AGENT AND ANTICANCER AGENT CONTAINING LIGNANS ORIGINATING IN HONGDOUSHAN
(FR) AGENT HYPOGLYCEMIQUE, AGENT PROTECTEUR HEPATIQUE ET AGENT ANTICANCER CONTENANT DE LIGANDS PROVENANT D'UNE PLANTE DE HONGDOUSHAN
(JA) 紅豆杉由来リグナン類を含む血糖降下剤、肝臓保護薬、抗ガン剤
Abstract: front page image
(EN)Drugs containing taxiresinol, (7’R)-7’-hydroxylariciresinol, secoisolariciresinol and isotaxiresinol, which are lignans contained in hongdoushan, as the active ingredients. Drugs containing an extract, which is obtained by extracting a hongdoushan plant with water and further extracting the obtained extract with an organic solvent, as the active ingredient. These drugs are useful particularly as a hyopglycermic agent, a liver protecting agent and an anticancer agent.
(FR)L'invention concerne des médicaments contenant un taxirésinol, (7'R)-7'-hydroxylaricirésinol, un sécoisolaricirésinol et un isotaxirésinol qui constituent des ligands contenus dans une plante de hongdoushan utilisés comme ingrédients actifs. Lesdits médicaments contiennent un extrait obtenu par extraction d'une plante de hongdoushan à l'aide d'eau, puis par extraction de l'extrait obtenu à l'aide d'un solvant organique utilisé comme ingrédient actif. Ces médicaments sont utilisés, en particulier, comme agent hypoglycémique, agent protecteur hépatique et agent anticancer
(JA)  紅豆杉に含まれるリグナン類である、タキシレシノール(Taxiresinol)、ヒドロキシラリシレシノール((7'R)-7'-Hydroxylariciresinol)、セコイソラリシレシノール(Secoisolariciresinol)、イソタキシレシノール(Isotaxiresinol)を有効成分とする医薬である。また、紅豆杉の植物体を水で抽出し、得られた水抽出物を有機溶媒により抽出して得られる抽出物を有効成分とする医薬である。これらは、特に、血糖降下剤、肝臓保護薬、抗ガン剤として有用である。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)