WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2004007671) METHODS OF IDENTIFYING COMPOUNDS THAT MODULATE IL-4 RECEPTOR-MEDIATED IgE SYNTHESIS UTILIZING A CLLD8 PROTEIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/007671    International Application No.:    PCT/US2003/021574
Publication Date: 22.01.2004 International Filing Date: 10.07.2003
Chapter 2 Demand Filed:    12.02.2004    
IPC:
A61K 38/17 (2006.01), G01N 33/68 (2006.01)
Applicants: RIGEL PHARMACEUTICALS, INC. [US/US]; 1180 Veterans Blvd., South San Francisco, CA 94080 (US) (For All Designated States Except US).
MASUDA, Esteban [CO/US]; (US) (For US Only).
KINSELLA, Todd, M. [US/US]; (US) (For US Only).
WARNER, Justin, E. [US/US]; (US) (For US Only).
KINOSHITA, Taisei [JP/US]; (US) (For US Only).
BENNETT, Mark, K. [US/US]; (US) (For US Only).
ANDERSON, David, C. [US/US]; (US) (For US Only)
Inventors: MASUDA, Esteban; (US).
KINSELLA, Todd, M.; (US).
WARNER, Justin, E.; (US).
KINOSHITA, Taisei; (US).
BENNETT, Mark, K.; (US).
ANDERSON, David, C.; (US)
Agent: PEASE, Ann; DORSEY & WHITNEY LLP, 4 Embarcadero Center, Suite 3400, San Francisco, CA 94111 (US)
Priority Data:
10/197,368 16.07.2002 US
Title (EN) METHODS OF IDENTIFYING COMPOUNDS THAT MODULATE IL-4 RECEPTOR-MEDIATED IgE SYNTHESIS UTILIZING A CLLD8 PROTEIN
(FR) PROCEDES D'IDENTIFICATION DE COMPOSES MODULANT LA SYNTHESE D'IGE DONT LE RECEPTEUR D'IL-4 ASSURE LA MEDIATION, AU MOYEN D'UNE PROTEINE CLLD8
Abstract: front page image
(EN)The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize a CLLD8 protein as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.
(FR)L'invention concerne des composés permettant de moduler la production d'IgE dont le récepteur d'IL-4 assure la médiation, ainsi que des processus associés induits par IL-4, des procédés et des kits d'identification de tels composés au moyen d'une protéine CLLD8 en tant qu'analyte de substitution et des procédés d'utilisation des composés dans une variété de contextes <i>in vitro</i>, <i>in vitro</i> et <i>ex vivo</i>.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)