WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2004007420) PROCESS FOR PRODUCING &agr;-METHYL-ß-KETO ESTER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/007420    International Application No.:    PCT/JP2003/008847
Publication Date: 22.01.2004 International Filing Date: 11.07.2003
Chapter 2 Demand Filed:    25.12.2003    
IPC:
B01J 21/18 (2006.01), B01J 23/44 (2006.01), C07C 67/317 (2006.01), C07C 67/343 (2006.01)
Applicants: MEIJI SEIKA KAISHA, LTD. [JP/JP]; 4-16, Kyobashi 2-chome, Chuo-ku, Tokyo 104-8002 (JP) (For All Designated States Except US).
NISHIZUKA, Toshio [JP/JP]; (JP) (For US Only).
KURIHARA, Hiroshi [JP/JP]; (JP) (For US Only)
Inventors: NISHIZUKA, Toshio; (JP).
KURIHARA, Hiroshi; (JP)
Agent: YOSHITAKE, Kenji; Kyowa Patent & Law Office, Room 323, Fuji Bldg., 2-3, Marunouchi 3-chome, Chiyoda-ku, Tokyo 100-0005 (JP)
Priority Data:
2002-202214 11.07.2002 JP
Title (EN) PROCESS FOR PRODUCING &agr;-METHYL-ß-KETO ESTER
(FR) PROCEDE DE PRODUCTION D'$G(A)-METHYL-$G(B)-CETOESTER
(JA) α−メチル−β−ケトエステルの製造法
Abstract: front page image
(EN)A process for efficiently producing an &agr;-methyl-ß-keto ester from a ß-keto ester as a starting material without using any toxic reagent or highly severe conditions. The process comprises dissolving pellet-form paraformaldehyde in a liquid mixture of a ß-keto ester and acetic anhydride, adding a hydrous lower alcohol, and conducting hydrolysis in a hydrogen atmosphere with the aid of a palladium-carbon catalyst.
(FR)L'invention concerne un procédé de production efficace d'un $g(a)-méthyl-$g(b)-cétoester à partir d'un $g(b)-cétoester en tant que matière de départ sans utiliser de réactif toxique ou sans que ce soit dans des conditions très difficiles. Ledit procédé consiste à dissoudre du paraformaldéhyde dans un mélange liquide d'un $g(b)-cétoester et d'anhydride acétique, à ajouter un alcool inférieur aqueux, et à mener à bien l'hydrolyse dans une atmosphère d'hydrogène à l'aide d'un catalyseur au palladium-carbone.
(JA)β−ケトエステルを原料に、毒性を有する試薬や特別に苛烈な条件を使わず、効率よくα−メチル−β−ケトエステルが製造できる方法が開示されている。この方法は、β−ケトエステルと無水酢酸との混合液にペレット状のパラホルムアルデヒドを溶解させ、含水低級アルコールを加え、水素雰囲気下、パラジウム−炭素触媒で加水素分解して効率よくα−メチル−β−ケトエステルを製造する。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)