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1. (WO2004006966) STEROID CONJUGATES, PREPARATION THEREOF AND THE USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/006966    International Application No.:    PCT/IB2003/002785
Publication Date: 22.01.2004 International Filing Date: 14.07.2003
Chapter 2 Demand Filed:    08.01.2004    
IPC:
A61K 47/48 (2006.01), A61K 49/00 (2006.01)
Applicants: MEDEXIS S.A. [GR/GR]; 4 Asklipiou Street, GR-145 68 Kryoneri (GR) (For All Designated States Except US).
CASTANAS, Elias [GR/GR]; (GR) (For US Only)
Inventors: CASTANAS, Elias; (GR)
Agent: CARLSSON, Eva; Internationalt Patent-Bureau A/S, Høje Taastrup Boulevard 23, DK-2630 Taastrup (DK)
Priority Data:
20020100335 16.07.2002 GR
Title (EN) STEROID CONJUGATES, PREPARATION THEREOF AND THE USE THEREOF
(FR) CONJUGUES STEROIDES, LEUR PREPARATION ET LEUR UTILISATION
Abstract: front page image
(EN)Conjugates comprising one or more steroids conjugated with one or more mammalian proteins are disclosed. The conjugates are useful for diagnosis or treatment of solid cancer and haematological malignancies. Further the conjugates exhibits a synergistic action together with a cytoskeleton acting drug such as Taxol°, which enable the treatment of cancers that otherwise would be non responsive to Taxol°.
(FR)L'invention concerne des conjugués comprenant un ou plusieurs stéroïdes conjugués avec une ou plusieurs protéines de mammifères. Les conjugués sont utilisés pour diagnostiquer ou traiter un cancer solide et des malignités hématologiques. Les conjugués font preuve, en outre, d'un effet synergistique doublé d'un effet sur le cytosquelette assuré par un médicament, notamment le Taxol, permettant le traitement de cancers qui ne réagiraient pas, autrement, au Taxol°.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)