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Machine translation
1. (WO2004006962) A TISSUE FACTOR BINDING IMMUNOCONJUGATE COMPRISING FACTOR VIIA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/006962    International Application No.:    PCT/DK2003/000481
Publication Date: 22.01.2004 International Filing Date: 09.07.2003
Chapter 2 Demand Filed:    19.01.2004    
IPC:
A61K 47/48 (2006.01), C07K 5/087 (2006.01), C07K 5/09 (2006.01), C07K 5/093 (2006.01), C12N 9/64 (2006.01)
Applicants: NOVO NORDISK A/S [DK/DK]; Novo Allé, DK-2880 Bagsværd (DK)
Inventors: BJØRN, Søren, E.; (DK).
NICOLAISEN, Else, Marie; (DK).
STEENSTRUP, Thomas, D.; (DK)
Priority Data:
PA 2002 01099 12.07.2002 DK
Title (EN) A TISSUE FACTOR BINDING IMMUNOCONJUGATE COMPRISING FACTOR VIIA
(FR) COMPOSE DE LIAISON AU FACTEUR TISSULAIRE
Abstract: front page image
(EN)The present invention relates to novel compounds which bind to inhibit the activity of tissue factor (TF) and mediates a cytolytic immune response. The compounds comprise factor VIIA and an immunostimulatory effector domain. The invention also relates to pharmaceutical compositions comprising the compounds as well as their use in the treatment of prophylaxis of diseases or disorders related to pathophysiological tissue factor activity including cancer, inflammation, atherosclerosis and ischemia/reperfusion.
(FR)L'invention concerne des nouveaux composés qui se lient au facteur tissulaire (FT), inhibent son activité et participent indirectement à la réponse immunitaire cytolytique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)