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Machine translation
1. (WO2004006925) N-SULFONYLPIPERIDINES AS METALLOPROTEINASE INHIBITORS (TACE)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/006925    International Application No.:    PCT/GB2003/002959
Publication Date: 22.01.2004 International Filing Date: 09.07.2003
Chapter 2 Demand Filed:    20.01.2004    
IPC:
C07D 211/96 (2006.01), C07D 401/12 (2006.01), C07D 401/14 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; Sodertalje, S-151 85 (SE) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, FR, GB, GD, GE, GH, GM, GR, HR, HU, ID, IE, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, SZ, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
ASTRAZENECA UK LIMITED [GB/GB]; 15 Stanhope Gate, London, Greater London W1K 1LN (GB) (MG only).
BURROWS, Jeremy, Nicholas [GB/GB]; (GB) (For US Only).
TUCKER, Howard [GB/GB]; (GB) (For US Only)
Inventors: BURROWS, Jeremy, Nicholas; (GB).
TUCKER, Howard; (GB)
Agent: ASTRAZENECA; Global Intellectual Property, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG (GB)
Priority Data:
0216379.8 13.07.2002 GB
Title (EN) N-SULFONYLPIPERIDINES AS METALLOPROTEINASE INHIBITORS (TACE)
(FR) N-SULFONYLPIPERIDINES UTILISES COMME INHIBITEURS DE METALLOPROTEINASE (TACE) (ENZYME DE CONVERSION DU FACTEUR DE NECROSE TUMORALE $G(A))
Abstract: front page image
(EN)Compounds of formula (1), wherein Z is -CONR15OH or -N(OH)CHO and X is -(CR9R10)t-Q-(CR11R12)u- (where t and u are independently 0 or 1 with the proviso that t and u cannot both be 0);are inhibitors of metalloproteinases and in particular TACE.
(FR)Cette invention a trait à des composés, correspondant à la formule (I), et qui sont des inhibiteurs des métalloprotéase, notamment de l'enzyme de conversion du facteur de nécrose tumorale $g(a) (TACE). Dans cette formule, Z représente -CONR15OH ou -N(OH)CHO et X représente -(CR9R10)t-Q-(CR11R12)u- (les valeurs de t et de u étant, de façon indépendante de 0 ou de 1, à la condition que t et u ne puissent pas valoir tous les deux 0).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)