Processing

Please wait...

Settings

Settings

Goto Application

1. WO2004005925 - DIAGNOSTICS METHOD

Publication Number WO/2004/005925
Publication Date 15.01.2004
International Application No. PCT/GB2003/002936
International Filing Date 07.07.2003
IPC
G01N 33/50 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
CPC
G01N 33/505
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
5005involving human or animal cells
5008for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
5044involving specific cell types
5047Cells of the immune system
505involving T-cells
G01N 33/5695
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
569for microorganisms, e.g. protozoa, bacteria, viruses
56911Bacteria
5695Mycobacteria
Applicants
  • ISIS INNOVATION LIMITED [GB]/[GB] (AllExceptUS)
  • LALVANI, Ajit [GB]/[GB] (UsOnly)
  • EWER, Katie [GB]/[GB] (UsOnly)
Inventors
  • LALVANI, Ajit
  • EWER, Katie
Agents
  • IRVINE, Jonquil, Claire
Priority Data
0215710.505.07.2002GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DIAGNOSTICS METHOD
(FR) METHODE DIAGNOSTIQUE
Abstract
(EN)
Method of diagnosing in an individual recent exposure to an agent which is a pathogen, vaccine or any other moiety which induces a cellular response, said method comprising determining in vitro whether the T cells of the individual recognise a protein from said agent having a length of at least 30 amino acids, to a greater extent than one or more peptide epitopes from the agent, a greater extent of recognition of the protein indicating that the individual has recently been exposed to the agent.
(FR)
L'invention concerne une méthode de diagnostic chez un sujet d'une exposition récente à un agent, tel qu'un pathogène, un vaccin ou un autre fragment induisant une réponse cellulaire. Ladite méthode consiste à déterminer in vitro si les lymphocytes T du sujet reconnaissent une protéine dudit agent, d'une longueur d'au moins 30 aminoacides, dans des proportions plus importantes qu'un ou plusieurs épitopes peptidiques de l'agent, une reconnaissance plus importante de la protéine indiquant que le sujet a été exposé récemment audit agent.
Also published as
NZ537331
PH1-2005-500022
PH12005500022
ZA200500056
Latest bibliographic data on file with the International Bureau