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Machine translation
1. (WO2004005923) RABS AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/005923    International Application No.:    PCT/US2003/021382
Publication Date: 15.01.2004 International Filing Date: 09.07.2003
IPC:
C07K 14/47 (2006.01), G01N 33/50 (2006.01)
Applicants: EXELIXIS, INC. [US/US]; P.O. Box 511, 170 Harbor Way, South San Francisco, CA 94083-0511 (US) (For All Designated States Except US).
COSTA, Michael [US/US]; (US) (For US Only).
MAXWELL, Mark, E. [US/US]; (US) (For US Only).
LACKNER, Mark, R. [US/US]; (US) (For US Only).
HUNG, Tak [CN/US]; (US) (For US Only).
O'BRIEN, Carol, L. [US/US]; (US) (For US Only).
HEUER, Timothy, S. [US/US]; (US) (For US Only).
LICKTEIG, Kim [US/US]; (US) (For US Only)
Inventors: COSTA, Michael; (US).
MAXWELL, Mark, E.; (US).
LACKNER, Mark, R.; (US).
HUNG, Tak; (US).
O'BRIEN, Carol, L.; (US).
HEUER, Timothy, S.; (US).
LICKTEIG, Kim; (US)
Agent: SHAYESTEH, Laleh; Exelixis, Inc., P. O. Box 511, 170 Harbor Way, South San Francisco, CA 94083-0511 (US)
Priority Data:
60/394,992 10.07.2002 US
60/410,988 16.09.2002 US
Title (EN) RABS AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
(FR) RABS UTILISES COMME MODIFICATEURS DE LA VOIE P53 ET LEURS PROCEDES D'UTILISATION
Abstract: front page image
(EN)Human RAB genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of RAB are provided.
(FR)Les gènes RAB humains sont identifiés comme modulateurs de la voie p53 et sont donc des cibles thérapeutiques pour les troubles liés au dysfonctionnement de la voie p53. Les procédés d'identification des modulateurs de p53 comprennent le criblage d'agents qui modulent l'activité de RAB.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)