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Machine translation
1. (WO2004005890) COMPOSITIONS, METHODS AND KITS RELATING TO ANTI-PLATELET AUTOANTIBODIES AND INHIBITORS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/005890    International Application No.:    PCT/US2003/021304
Publication Date: 15.01.2004 International Filing Date: 03.07.2003
Chapter 2 Demand Filed:    21.01.2004    
IPC:
C07K 16/00 (2006.01), C07K 16/28 (2006.01), G01N 33/86 (2006.01)
Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; 3160 Chestnut Street, Suite 200, Philadelphia, PA 19104 (US) (For All Designated States Except US).
SIEGEL, Donald, L. [US/US]; (US) (For US Only)
Inventors: SIEGEL, Donald, L.; (US)
Agent: ALVAREZ, Raquel, M.; Morgan, Lewis & Bockius LLP, 1701 Market Street, Philadelphia, PA 19103 (US)
Priority Data:
60/394,352 03.07.2002 US
60/411,694 18.09.2002 US
Title (EN) COMPOSITIONS, METHODS AND KITS RELATING TO ANTI-PLATELET AUTOANTIBODIES AND INHIBITORS THEREOF
(FR) COMPOSITIONS, PROCEDES ET KITS AYANT TRAIT A DES AUTO-ANTICORPS ANTIPLAQUETTAIRES ET LEURS INHIBITEURS
Abstract: front page image
(EN)The present invention relates to novel methods of identifying and producing an anti-platelet autoantibody. More preferably, the invention relates to identification and production of a human monoclonal anti-platelet autoantibody. Additionally, the invention relates to methods for producing and identifying inhibitors of an anti-platelet autoantibody binding with a platelet, or a platelet component. Moreover, the invention relates to methods for treating or alleviating a disease, disorder or condition mediated by an anti-platelet autoantibody specifically binding with a platelet, or a component thereof, such as, but not limited to, idiopathic thrombocytopenic purpura, among others.
(FR)La présente invention se rapporte à de nouveaux procédés d'identification et de production d'un auto-anticorps antiplaquettaire. L'invention se rapporte de préférence à l'identification et à la production d'un auto-anticorps antiplaquettaire monoclonal humain. L'invention se rapporte en outre à des procédés de production et d'identification d'inhibiteurs d'un auto-anticorps antiplaquettaire se liant à une plaquette ou à un composant plaquettaire. L'invention se rapporte par ailleurs à des méthodes de traitement ou de soulagement d'une maladie, d'un trouble ou d'un état induit(e) par un auto-anticorps antiplaquettaire se liant spécifiquement à une plaquette ou à son composant, dont entre autres un purpura thrombocytopénique idiopathique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)