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1. (WO2004005551) ANTISENSE MODULATION OF NF-KAPPA-B P50 SUBUNIT EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/005551    International Application No.:    PCT/US2003/019092
Publication Date: 15.01.2004 International Filing Date: 18.06.2003
Chapter 2 Demand Filed:    29.01.2004    
IPC:
A61K 38/00 (2006.01), C07H 21/04 (2006.01), C12N 15/11 (2006.01)
Applicants: ISIS PHARMACEUTICALS, INC. [US/US]; 2292 Faraday Avenue, Carlsbad, CA 92008 (US) (For All Designated States Except US).
BAKER, Brenda, F. [US/US]; (US) (For US Only).
FREIER, Susan, M. [US/US]; (US) (For US Only).
DOBIE, Kenneth, W. [US/US]; (US) (For US Only)
Inventors: BAKER, Brenda, F.; (US).
FREIER, Susan, M.; (US).
DOBIE, Kenneth, W.; (US)
Agent: LICATA, Jane, Massey; Licata & Tyrrell P.C., 66 East Main Street, Marlton, NJ 08053 (US)
Priority Data:
10/189,256 02.07.2002 US
Title (EN) ANTISENSE MODULATION OF NF-KAPPA-B P50 SUBUNIT EXPRESSION
(FR) MODULATION ANTISENS DE L'EXPRESSION DE LA SOUS-UNITE DE NF-KAPPA-B P50
Abstract: front page image
(EN)Antisense compounds, compositions and methods are provided for modulating the expression of NF-kappa-B p50 subunit. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding NF-kappa-B p50 subunit. Methods of using these compounds for modulation of NF-kappa-B p50 subunit expression and for treatment of diseases associated with expression of NF-kappa-B p50 subunit are provided.
(FR)Composés anti-sens, compositions et procédés servant à moduler l'expression de la sous-unité de NF-kappa-B p50. Ces compositions contiennent des composés anti-sens, en particulier, des oligonucléotides anti-sens, ciblés vers des acides nucléiques codant la sous-unité de NF-kappa-B p50. Procédés servant à utiliser ces composés afin de moduler l'expression de la sous-unité de NF-kappa-B p50 et de traiter des maladies associées à l'expression de cette sous-unité de NF-kappa-B p50.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)