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Machine translation
1. (WO2004005538) METHOD OF SCREENING ANTICANCER AGENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/005538    International Application No.:    PCT/JP2003/008470
Publication Date: 15.01.2004 International Filing Date: 03.07.2003
Chapter 2 Demand Filed:    04.08.2003    
IPC:
C12Q 1/34 (2006.01)
Applicants: HONJO, Tasuku [JP/JP]; (JP).
TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP/JP]; 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 541-0045 (JP) (For All Designated States Except US).
YOSHIKAWA, Kiyotsugu [JP/JP]; (JP) (For US Only)
Inventors: HONJO, Tasuku; (JP).
YOSHIKAWA, Kiyotsugu; (JP)
Agent: KOBAYASHI, Hiroshi; c/o ABE, IKUBO & KATAYAMA, Fukuoka Bldg. 9th Fl., 8-7, Yaesu 2-chome, Chuo-ku, Tokyo 104-0028 (JP)
Priority Data:
2002-196764 05.07.2002 JP
Title (EN) METHOD OF SCREENING ANTICANCER AGENT
(FR) METHODE DE CRIBLAGE D'UN AGENT ANTICANCEREUX
(JA) 抗癌剤のスクリーニング方法
Abstract: front page image
(EN)It is intended to provide a method of screening an anticancer agent, an anticancer agent obtained by using this screening method, etc. A compound obtained by using the screening method as described above and a screening kit is usable as an anticancer agent and a mutation-tranaser promoter. Moreover, use of a method of detecting a mutation in somatic cells to be employed herein makes it possible to efficiently construct a mutant protein carrying a mutation transferred thereinto in cells.
(FR)La présente invention concerne une méthode de criblage d'un agent anticancéreux, un agent anticancéreux obtenu au moyen de ladite méthode de criblage et autres. Un composé obtenu à l'aide de la méthode de criblage selon l'invention et d'une trousse de criblage peut être utilisé en tant qu'agent anticancéreux et que promoteur de transfert d'une mutation. De surcroît, le fait d'utiliser une méthode de détection d'une mutation dans des cellules somatiques devant être utilisées, permet de construire efficacement une protéine mutante porteuse d'une mutation transférée dans des cellules.
(JA)本発明は、抗癌剤のスクリーニング方法、該スクリーニング方法を用いることにより得られる抗癌剤などを提供する。本発明のスクリーニング方法およびスクリーニング用キットを用いることにより得られる化合物は抗癌剤および変異導入促進剤として用いることができる。また、本発明で用いられる体細胞突然変異の検出方法を利用することにより、細胞内で効率的に変異が導入された変異タンパク質を作製することができる。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)