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Machine translation
1. (WO2004003172) ESM-1 GENE DIFFERENTIALLY EXPRESSED IN ANGIOGENESIS, ANTAGONISTS THEREOF, AND METHODS OF USING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/003172    International Application No.:    PCT/US2003/020721
Publication Date: 08.01.2004 International Filing Date: 01.07.2003
Chapter 2 Demand Filed:    29.01.2004    
IPC:
A61K 38/00 (2006.01), C07K 14/47 (2006.01)
Applicants: PHARMACIA CORPORATION [US/US]; 700 Chesterfield Parkway West, Chesterfield, MO 63017-1732 (US) (For All Designated States Except US).
GRIGGS, David, W. [US/US]; (US) (For US Only).
HEAD, Richard, D. [US/US]; (US) (For US Only).
MAZZARELLA, Richard [US/US]; (US) (For US Only).
WEINSTEIN, Edward, J. [US/US]; (US) (For US Only)
Inventors: GRIGGS, David, W.; (US).
HEAD, Richard, D.; (US).
MAZZARELLA, Richard; (US).
WEINSTEIN, Edward, J.; (US)
Agent: BAUER, S., Christopher; Pharmacia Corporation, Corporate Patent Department, P.O. Box 1027, Chesterfield, MO 63006 (US).
NENOW, Lydia N.; Harness, Dickey & Pierce PLC, 7700 Bonhomme, Suite 400, St. Louis, MI 63105 (US)
Priority Data:
60/392,784 01.07.2002 US
Title (EN) ESM-1 GENE DIFFERENTIALLY EXPRESSED IN ANGIOGENESIS, ANTAGONISTS THEREOF, AND METHODS OF USING THE SAME
(FR) GENE ESM-1 EXPRIME DIFFERENTIELLEMENT DANS L'ANGIOGENESE, ANTAGONISTES DE DERNIER ET METHODES D'UTILISATION CORRESPONDANTES
Abstract: front page image
(EN)The invention relates a nucleic acid and its encoded polypeptide ESM-1, whose expression is modulated in angiogenesis and oncogenesis. The invention also relates to antibodies having specificity for said polypeptide. The present invention also relates to antisense molecules. The invention further relates to methods useful for treating or modulating angiogenesis in mammals in need of such biological effect.
(FR)La présente invention concerne un acide nucléique et son polypeptide codé ESM-1, dont l'expression est modulée dans l'angiogenèse et l'oncogenèse; des anticorps ayant une spécificité pour ledit polypeptide; des molécules antisens; et des méthodes utiles pour traiter ou moduler l'angiogenèse chez des mammifères nécessitant un tel effet biologique.
Designated States: JP, US.
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR).
Publication Language: English (EN)
Filing Language: English (EN)