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1. (WO2004003152) SOS1 INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/003152    International Application No.:    PCT/US2003/020293
Publication Date: 08.01.2004 International Filing Date: 25.06.2003
Chapter 2 Demand Filed:    30.12.2003    
C07K 14/47 (2006.01), C12N 15/11 (2006.01)
Applicants: CHIRON CORPORATION [US/US]; Intellectual Property, R338, P.O. Box 8097, Emeryville, CA 94662-8097 (US) (For All Designated States Except US).
FANTL, Wendy, J. [US/US]; (US) (For US Only).
JAITNER, Birgit, K. [US/US]; (US) (For US Only)
Inventors: FANTL, Wendy, J.; (US).
JAITNER, Birgit, K.; (US)
Agent: CHIRON CORPORATION; Intellectual Property, R338, P.O. Box 8097, Emeryville, CA 94662-8097 (US)
Priority Data:
60/391,993 26.06.2002 US
Abstract: front page image
(EN)Inhibitors of human Sos1, including antisense oligonucleotides, methods, and compositions specific for human Sos1, are provided. Methods of using the compositions for modulating Sos1 expression and for regulating cell growth, particularly tumor cell growth, are also provided.
(FR)L'invention concerne des inhibiteurs de protéines Sos1 d'origine humaine, y compris des oligonucléotides antisens, des procédés et des compositions spécifiques desdites protéines. Elle concerne aussi des procédés d'utilisation de ces compositions afin de moduler l'expression de Sos1 et de réguler la croissance cellulaire, en particulier la croissance de cellules tumorales.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)