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1. (WO2004003012) NOVEL VARIANTS OF THE PAPM POLYPEPTIDE OF BACTERIA OF GENUS STREPTOMYCES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/003012    International Application No.:    PCT/FR2003/001926
Publication Date: 08.01.2004 International Filing Date: 23.06.2003
Chapter 2 Demand Filed:    20.01.2004    
IPC:
A61K 38/00 (2006.01), C07K 5/02 (2006.01), C12N 9/10 (2006.01)
Applicants: AVENTIS PHARMA S.A. [FR/FR]; 20, avenue Raymond Aron, F-92160 Antony (FR) (For All Designated States Except US).
BAMAS-JACQUES, Nathalie [FR/FR]; (FR) (For US Only).
THIBAUT, Denis [FR/FR]; (FR) (For US Only).
FAMECHON, Alain [FR/FR]; (FR) (For US Only)
Inventors: BAMAS-JACQUES, Nathalie; (FR).
THIBAUT, Denis; (FR).
FAMECHON, Alain; (FR)
Agent: DERNONCOUR, Roxane; Aventis Pharma S.A., Direction Brevets, 20, avenue Raymond Aron, F-92165 Antony Cedex (FR)
Priority Data:
02/08057 28.06.2002 FR
Title (EN) NOVEL VARIANTS OF THE PAPM POLYPEPTIDE OF BACTERIA OF GENUS STREPTOMYCES
(FR) VARIANTS DU POLYPEPTIDE PAPM DE BACTERIES DU GENRE STREPTOMYCES.
Abstract: front page image
(EN)The invention concerns novel variants of the PapM polypeptide of bacteria of genus Streptomycetes having substrate selectivity and/or enhanced efficacy relative to the wild-type polypeptide. The invention also concerns nucleic acids coding for said variants, micro-organisms incorporating said nucleic acids and their use for producing streptogramin B components.
(FR)La présente invention concerne de nouveaux variants du polypeptide PapM de bactéries du genre Streptomycetes possédant une sélectivité de substrat et/ou une efficacité améliorée par rapport au polypeptide de type sauvage. Elle se rapporte également aux acides nucléiques codant pour ces variants, aux microorganismes incorporant ces acides nucléiques et leur utilisation pour la production de composantes B des Streptogramines.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)