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Machine translation
1. (WO2004003008) PEPTIDES FOR INDUCING APOPTOSIS IN TUMOR CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/003008    International Application No.:    PCT/EP2003/006958
Publication Date: 08.01.2004 International Filing Date: 01.07.2003
Chapter 2 Demand Filed:    02.02.2004    
IPC:
A61K 38/00 (2006.01), C07K 7/08 (2006.01), C07K 14/00 (2006.01), C07K 14/47 (2006.01)
Applicants: DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS [DE/DE]; Im Neuenheimer Feld 280, 69120 Heidelberg (DE) (For All Designated States Except US).
BUTZ, Karin [DE/DE]; (DE) (For US Only).
CRNKOVIC-MERTENS, Irena [HR/DE]; (DE) (For US Only).
HOPPE-SEYLER, Felix [DE/DE]; (DE) (For US Only).
RAUSCH, Christian [AT/DE]; (DE) (For US Only)
Inventors: BUTZ, Karin; (DE).
CRNKOVIC-MERTENS, Irena; (DE).
HOPPE-SEYLER, Felix; (DE).
RAUSCH, Christian; (DE)
Agent: ISENBRUCK, Günter; Isenbruck-Bösl-Hörschler-Wichmann-Huhn, Theodor-Heuss-Anlage 12 68165 Mannheim (DE)
Priority Data:
02014074.5 01.07.2002 EP
Title (EN) PEPTIDES FOR INDUCING APOPTOSIS IN TUMOR CELLS
(FR) PEPTIDES INDUISANT L'APOPTOSE DANS LES CELLULES TUMORALES
Abstract: front page image
(EN)The present invention relates to peptides which interact with IAPs. IAPs are highly expressed in tumor cells which fail to undergo apoptosis. By binding to IAPs, the peptides of the present invention release tumor cells from the apoptosis block and thus provide a new tool for effective cancer therapy.
(FR)L'invention concerne des peptides entrant en interaction avec les inhibiteurs de protéines de l'apoptose. Ces inhibiteurs ont une expression marquée dans les cellules tumorales qui échappent à l'apoptose. En se liant avec lesdits inhibiteurs, les peptides considérés libèrent les cellules tumorales du blocage de l'apoptose et constituent ainsi un outil efficace pour la thérapie anticancéreuse.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)