WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2004002999) MODIFIED 2' AND 3' -NUCLEOSIDE PRODUGS FOR TREATING FLAVIRIDAE INFECTIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/002999    International Application No.:    PCT/IB2003/003246
Publication Date: 08.01.2004 International Filing Date: 27.06.2003
Chapter 2 Demand Filed:    27.01.2004    
IPC:
A61K 31/7056 (2006.01), A61K 31/706 (2006.01), A61K 31/7064 (2006.01), A61K 31/7076 (2006.01), A61P 31/14 (2006.01), C07H 19/00 (2006.01), C07H 19/04 (2006.01), C07H 19/044 (2006.01), C07H 19/048 (2006.01), C07H 19/052 (2006.01), C07H 19/056 (2006.01), C07H 19/06 (2006.01), C07H 19/10 (2006.01), C07H 19/12 (2006.01), C07H 19/14 (2006.01), C07H 19/16 (2006.01), C07H 19/20 (2006.01), C07H 19/22 (2006.01), C07H 19/23 (2006.01)
Applicants: IDENIX (CAYMAN) LIMITED; Walker Secretaries, Walker House, Grand Cayman (KY) (For All Designated States Except US).
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE [FR/FR]; 3, rue Michel-Ange, F-75794 Paris Cédex 16 (FR) (For All Designated States Except US).
UNIVERSITA DEGLI STUDI DI CAGLIARI [IT/IT]; Dip. Biologia Sperimentale, Sezione di Microbiologia, Cittadella Universitaria SS 554, Km. 4.500, I-09042 Monserrato (IT) (For All Designated States Except US).
SOMMADOSSI, Jean-Pierre [FR/US]; (US) (For US Only).
LA COLLA, Poalo [IT/IT]; (IT) (For US Only).
STORER, Richard [GB/GB]; (GB) (For US Only).
GOSSELIN, Gilles [FR/FR]; (FR) (For US Only)
Inventors: SOMMADOSSI, Jean-Pierre; (US).
LA COLLA, Poalo; (IT).
STORER, Richard; (GB).
GOSSELIN, Gilles; (FR)
Agent: KNOWLES, Sherry, M.; King & Spalding LLP, 191 Peachtree St., Atlanta, GA 30303-1763 (US)
Priority Data:
60/392,350 28.06.2002 US
60/392,351 28.06.2002 US
60/466,194 28.04.2003 US
60/470,949 14.05.2003 US
Title (EN) MODIFIED 2' AND 3' -NUCLEOSIDE PRODUGS FOR TREATING FLAVIRIDAE INFECTIONS
(FR) PROMEDICAMENTS A NUCLEOSIDES 2' ET 3' DESTINES A TRAITER LES INFECTIONS AUX FLAVIVIRUS
Abstract: front page image
(EN)2' and/or 3' prodrugs of l', 2', 3' or 4'-branchednucleosides, and their pharmaceutically acceptable salts and derivatives are described. These prodrugs are useful in the prevention and treatment of Flaviviridae infections, including HCV infection, and other related conditions. Compounds and compositions of the prodrugs of the present invention are described. Methods and uses are also provided that include the administration of an effective amount of the prodrugs of the present invention, or their pharmaceutically acceptable salts or derivatives. These drugs may optionally be administered in combination or alteration with further anti-viral agents to prevent or treat Flaviviridae infections and other related conditions.
(FR)Promédicaments 2' et/ou 3' de nucléosides à branches 1', 2', 3' ou 4' ainsi que leurs sels pharmaceutiquement acceptables et leurs dérivés. Ces promédicaments sont utiles dans la prévention et le traitement des infections par les flavivirus, y compris l'infection par le virus de l'hépatite C et d'autres états liés à ces maladies. L'invention comprend une description des composés et des compositions de ces promédicaments, ainsi que des procédés et de l'utilisation, y compris l'administration d'une quantité efficace de promédicaments de l'invention ou de leurs sels ou dérivés efficaces. Ces médicaments peuvent éventuellement être administrés en combinaison ou en alternance avec d'autres agents antiviraux, à des fins de prévention ou de traitement des infections aux flavivivirus et d'autres états qui y sont liés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)