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1. (WO2004002995) PHOSPHORAMIDITES FOR COUPLING OLIGONUCLEOTIDES TO [2 + 2] PHOTOREACTIVE GROUPS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/002995    International Application No.:    PCT/IB2003/002514
Publication Date: 08.01.2004 International Filing Date: 27.06.2003
Chapter 2 Demand Filed:    22.01.2004    
IPC:
C07F 9/24 (2006.01), C07F 9/553 (2006.01), C07F 9/6503 (2006.01), C07F 9/6506 (2006.01), C07H 21/00 (2006.01)
Applicants: AMERSHAM BIOSCIENCES AB [SE/SE]; Bjorkgatan 30, S-751 84 Uppsala (SE)
Inventors: BRUSH, Charles, K.; (US).
ELGHANIAN, Robert; (US).
XU, Yanzheng; (US)
Agent: RONNING, Royal, N., Jr.; Amersham Biosciences Corp, 800 Centennial Avenue, Piscataway, NJ 08855 (US).
ROLLINS, Anthony; Amersham plc., Amersham Place, Little Chalfont, Bucks, HP7 9LL (GB)
Priority Data:
10/185,279 28.06.2002 US
Title (EN) PHOSPHORAMIDITES FOR COUPLING OLIGONUCLEOTIDES TO [2 + 2] PHOTOREACTIVE GROUPS
(FR) PHOSPHORAMIDITES CONCUES POUR COUPLER DES OLIGONUCLEOTIDES A DES GROUPES PHOTOACTIFS [2 + 2]
Abstract: front page image
(EN)Photoreactive phosphoramidites useful for attaching photoreactive sites to nucleic acids and oligonucleotides are synthesized. The resultant nucleic acid or oligonucleotide probes incorporating the photoreactive sites are then attached to a polymer-coated support by a [2 + 2] cycloaddition to form a microarray.
(FR)La présente invention concerne la synthèse de phosphoramidites photoréactives qui sont utilisées pour relier des sites photoréactifs à des acides nucléiques et à des oligonucléotides. Les sondes d'acides nucléiques ou d'oligonucléotides résultantes qui intègrent les sites photoréactifs sont ensuite reliées à un support à revêtement polymère au moyen d'une cycloaddition [2 + 2],afin de former un microréseau.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)