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1. (WO2004002950) SULFENYL COMPOUND, LABELING REAGENT, AND METHOD OF ANALYZING PEPTIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/002950    International Application No.:    PCT/JP2003/004308
Publication Date: 08.01.2004 International Filing Date: 03.04.2003
Chapter 2 Demand Filed:    12.09.2003    
IPC:
C07C 313/08 (2006.01), G01N 33/68 (2006.01)
Applicants: SHIMADZU CORPORATION [JP/JP]; 1, Nishinokyo-Kuwabaracho, Nakagyo-ku, Kyoto-shi, Kyoto 604-8511 (JP) (For All Designated States Except US).
KUYAMA, Hiroki [JP/JP]; (JP) (For US Only).
ANDO, Eiji [JP/JP]; (JP) (For US Only).
NISHIMURA, Osamu [JP/JP]; (JP) (For US Only)
Inventors: KUYAMA, Hiroki; (JP).
ANDO, Eiji; (JP).
NISHIMURA, Osamu; (JP)
Agent: OKADA, Masahiro; Okada & Co., 12th Shinko Bldg. 10F, 1-6, Zaimoku-cho, Chuo-ku, Osaka-shi, Osaka 540-0010 (JP)
Priority Data:
2002-191496 28.06.2002 JP
2002-191497 28.06.2002 JP
Title (EN) SULFENYL COMPOUND, LABELING REAGENT, AND METHOD OF ANALYZING PEPTIDE
(FR) COMPOSE SULFENYLE, REACTIF DE MARQUAGE. ET PROCEDE D'ANALYSE DE PEPTIDE
(JA) スルフェニル化合物、ラベル化試薬、及びペプチドの解析方法
Abstract: front page image
(EN)A sulfenyl compound represented by the general formula R-S-X (1) (wherein R represents an organic group having at least one constituent element labeled with an isotope; and X represents a leaving group); a labeling reagent containing the compound; and a method of peptide analysis which comprises using the labeling reagent. Preferably, the organic group R comprises as constituent elements carbon, hydrogen, and nitrogen and optionally contains oxygen and/or phosphorus, and the isotope is a stable one selected from the group consisting of 2H, 13C, 15N, 17O, and 18O.
(FR)L'invention concerne un composé sulfényle de formule générale R-S-X (1). Dans cette formule, R est un groupe organique ayant au moins un élément constitutif marqué par un isotope; et X est un groupe partant. L'invention concerne également un réactif de marquage renfermant le composé et un procédé d'analyse de peptide qui consiste à utiliser le réactif. De préférence, le groupe organique R renferme les éléments suivants: carbone, hydrogène et azote, et éventuellement oxygène et/ou phosphore. L'isotope est stable, appartenant au groupe constitué de 2H, 13C, 15N, 17O, et 18O.
(JA)(1)一般式:R-S-X(I)(式中、Rは、同位体で標識された少なくとも1つの構成元素を有する有機基を表し、Xは脱離基を表す。)で表されるスルフェニル化合物、それを含むラベル化試薬、及びそのラベル化試薬を用いるペプチドの解析法。好ましくは、前記有機基Rは構成元素としてC、H、N、場合によりO及び/又はpを含み、前記同位体は、2H、13C、15N、17O、18Oからなる群から選ばれる安定同位体である。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)