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Machine translation
1. (WO2004002945) (E)-1-[[(2E, 4E)-1-HEXYL-2,4-OCTADECADIENYL]OXY]-2-HYDROXYDIAZINE AND A PHARMACEUTICAL COMPOSITION FOR TREATING HEPATITIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/002945    International Application No.:    PCT/KR2003/001278
Publication Date: 08.01.2004 International Filing Date: 28.06.2003
Chapter 2 Demand Filed:    29.01.2004    
IPC:
C07C 245/02 (2006.01)
Applicants: BIOKOREA CO., LTD [KR/KR]; #710 SVI Medison annex bldg., 997-10 Dachi-dong, Kangnam-ku, Seoul 135-280 (KR) (For All Designated States Except US).
LEA, Young-Sung [KR/KR]; (KR) (For US Only).
AHN, Dong-Ho [KR/KR]; (KR) (For US Only).
LIM, Yoong-Ho [KR/KR]; (KR) (For US Only).
YOON, Seung-Kew [KR/KR]; (KR) (For US Only).
KIM, Man-Bae [KR/KR]; (KR) (For US Only).
KIM, Nam-Jin [KR/KR]; (KR) (For US Only).
CHANG, Eun-Joo [KR/KR]; (KR) (For US Only).
LEE, Min-Kyung [KR/KR]; (KR) (For US Only)
Inventors: LEA, Young-Sung; (KR).
AHN, Dong-Ho; (KR).
LIM, Yoong-Ho; (KR).
YOON, Seung-Kew; (KR).
KIM, Man-Bae; (KR).
KIM, Nam-Jin; (KR).
CHANG, Eun-Joo; (KR).
LEE, Min-Kyung; (KR)
Agent: SON, Min; 19th Floor, City Air Tower, 159-9 Samsung-dong, Gangnam-gu, Seoul 135-973 (KR)
Priority Data:
10-2002-0037749 29.06.2002 KR
Title (EN) (E)-1-[[(2E, 4E)-1-HEXYL-2,4-OCTADECADIENYL]OXY]-2-HYDROXYDIAZINE AND A PHARMACEUTICAL COMPOSITION FOR TREATING HEPATITIS
(FR) (E)-1-{[(2E,4E)-1-HEPTYLHEPTADECA-2,4-DIENYL]OXY}-2-HYDROXYDIAZENE ET COMPOSITION PHARMACEUTIQUE VISANT A TRAITER L'HEPATITE
Abstract: front page image
(EN)Disclosed are a (E)-1-[[(2E,4E)-1-hexyl-2,4-octadecadienyl]oxy]-2­hydroxydiazine compound represented by Chemical Formula I, below, or its pharmaceutically acceptable base addition salt, a method of preparing the compound, and a pharmaceutical composition comprising the compound for treating or preventing hepatitis. [Chemical Formula I] The compound of the present invention has an inhibitory effect on HBV activity as well as being effective in reducing HBV levels. Therefore, the compound of the present invention is very useful as a therapeutic agent for treatment of hepatitis.
(FR)La présente invention concerne un composé (E)-1-{[(2E,4E)-1-hexyl-2,4-octadécadienyl]oxy}-2-hydroxydiazine représenté par la formule chimique (I), ou son sel d'addition de base pharmaceutiquement acceptable, une méthode de préparation de ce composé et une composition pharmaceutique comprenant le composé et servant à traiter ou prévenir l'hépatite. Le composé de cette invention présente un effet inhibiteur sur l'activité du virus de l'hépatite B (HBV) et réduit efficacement les niveaux d'HBV. Le composé de la présente invention sert de ce fait d'agent thérapeutique dans le traitement de l'hépatite.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Korean (KO)