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1. (WO2004002524) PLACENTAL GROWTH FACTOR AS A TARGET FOR THE TREATMENT OF OSTEOPOROSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/002524    International Application No.:    PCT/EP2003/050274
Publication Date: 08.01.2004 International Filing Date: 27.06.2003
Chapter 2 Demand Filed:    17.01.2004    
IPC:
C07K 16/22 (2006.01), C07K 16/28 (2006.01)
Applicants: VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW [BE/BE]; Rijvisschestraat 120, B-9052 Zwijnaarde (BE) (For All Designated States Except US).
K.U.LEUVEN RESEARCH & DEVELOPMENT [BE/BE]; Groot Begijnhof 58-59, B-3000 Leuven (BE) (For All Designated States Except US).
CARMELIET, Peter [BE/BE]; (BE) (For US Only).
COLLEN, Désiré [BE/BE]; (BE) (For US Only).
BOUILLON, Roger [BE/BE]; (BE) (For US Only).
CARMELIET, Gertrudis [BE/BE]; (BE) (For US Only).
D. COLLEN RESEARCH FOUNDATION VZW [BE/BE]; Onderwijs en Navorsing Campus Gasthuisberg K.U.Leuven, Herestraat 49, B-3000 Leuven (BE) (For All Designated States Except US)
Inventors: CARMELIET, Peter; (BE).
COLLEN, Désiré; (BE).
BOUILLON, Roger; (BE).
CARMELIET, Gertrudis; (BE)
Agent: BIRD, Ariane; Bird Goën & Co, Klein Dalenstraat 42A, B-3020 Winksele (BE)
Priority Data:
02077591.2 28.06.2002 EP
Title (EN) PLACENTAL GROWTH FACTOR AS A TARGET FOR THE TREATMENT OF OSTEOPOROSIS
(FR) FACTEUR DE CROISSANCE PLACENTAIRE UTILISE COMME CIBLE DANS LE TRAITEMENT DE L'OSTEOPOROSE
Abstract: front page image
(EN)This invention relates to antagonists of placental growth factor and signalling thereof, pharmaceutical compositions containing such antagonists and the use of such antagonists to prevent bone loss or bone mass and to enhance bone healing including the treatment of conditions which present with low bone mass and/or bone defects in vertebrates, and particularly mammals, including humans.
(FR)L'invention concerne des antagonistes du facteur de croissance placentaire et leur signalisation, des compositions pharmaceutiques contenant de tels antagonistes et l'utilisation de tels antagonistes pour prévenir la déperdition osseuse ou la masse osseuse et pour favoriser la guérison osseuse, y compris le traitement d'états accompagnant une masse osseuse réduite et/ou des défectuosités osseuses chez des vertébrés et notamment des mammifères, y compris chez l'homme.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)