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Pub. No.:    WO/2004/002515    International Application No.:    PCT/JP2003/008167
Publication Date: 08.01.2004 International Filing Date: 27.06.2003
Chapter 2 Demand Filed:    18.08.2003    
A61K 31/7088 (2006.01), C07K 14/47 (2006.01), C12Q 1/37 (2006.01), G01N 33/68 (2006.01)
Applicants: TAKEDA CHEMICAL INDUSTRIES, LTD. [JP/JP]; 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 541-0045 (JP) (For All Designated States Except US).
NAKANISHI, Atsushi [JP/JP]; (JP) (For US Only).
IWASHITA, Hiroki [JP/JP]; (JP) (For US Only).
MORITA, Shigeru [JP/CA]; (CA) (For US Only).
MATSUMOTO, Tatsumi [JP/JP]; (JP) (For US Only).
YAMASAKI, Masashi [JP/JP]; (JP) (For US Only)
Inventors: NAKANISHI, Atsushi; (JP).
IWASHITA, Hiroki; (JP).
MORITA, Shigeru; (CA).
MATSUMOTO, Tatsumi; (JP).
YAMASAKI, Masashi; (JP)
Agent: KOBAYASHI, Hiroshi; c/o ABE, IKUBO & KATAYAMA, Fukuoka Bldg. 9th Fl., 8-7, Yaesu 2-chome, Chuo-ku, Tokyo 104-0028 (JP)
Priority Data:
2002-190732 28.06.2002 JP
(JA) 呼吸器疾患の診断・予防・治療剤
Abstract: front page image
(EN)It is intended to provide diagnostics/preventives/remedies, etc. for respiratory diseases. Namely, a compound or its salt promoting the activity of a protein having an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO:1, a compound or its salt promoting the expression of a gene of the above protein, an antisense nucleotide having a base sequence or a part thereof which is complementary or substantially complementary to the base sequence of a DNA encoding the above protein or its peptide fragment, an antibody against the above protein or its peptide fragment, etc. are usable as diagnostics/preventives/remedies, etc. for respiratory diseases.
(FR)L'invention concerne des agents diagnostiques/préventifs/curatifs etc. pour maladies respiratoires. Elle concerne notamment un composé ou son sel promouvant l'activité d'une protéine présentant une séquence d'acides aminés qui est la même ou sensiblement la même que celle de la séquence correspondant à SEQ ID NO:1, un composé ou son sel promouvant l'expression d'un gène de la protéine susmentionnée, un nucléotide antisens présentant une séquence de bases ou une partie de celle-ci qui est complémentaire ou sensiblement complémentaire de la séquence de bases d'un ADN codant la protéine susmentionnée ou son fragment peptidique, un anticorps dirigé contre la protéine susmentionnée ou son fragment peptidique, etc., lesquels peuvent être utilisés comme agents diagnostiques/préventifs/curatifs, etc. pour des maladies respiratoires.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)