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Machine translation
1. (WO2004002296) THERAPEUTIC METHODS FOR REDUCING FAT DEPOSITION AND TREATING ASSOCIATED CONDITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/002296    International Application No.:    PCT/US2003/020831
Publication Date: 08.01.2004 International Filing Date: 27.06.2003
IPC:
A61B 1/00 (2006.01), A61K 31/7088 (2006.01), A61K 38/46 (2006.01), A61K 45/00 (2006.01), A61K 48/00 (2006.01), C12Q 1/00 (2006.01), C12Q 1/34 (2006.01), C12Q 1/44 (2006.01), C12Q 1/68 (2006.01), G01N 33/53 (2006.01), G01N 33/92 (2006.01)
Applicants: SEQUENOM, INC. [US/US]; 3595 John Hopkins Court, San Diego, CA 92121 (US)
Inventors: ADAM, Gail, Isabel, Reid; (GB).
LANGDOWN, Maria, L.; (US).
DENISSENKO, Mikhail, F.; (US).
DENNIS, Edward; (US).
CANTOR, Charles; (US).
RUBIN, Byron; (US)
Agent: GRANT, BRUCE, D.; Morrison & Foerster LLP, 3811 Valley Center Drive, Suite 500, San Diego, CA 92130-2332 (US)
Priority Data:
60/392,362 27.06.2002 US
Title (EN) THERAPEUTIC METHODS FOR REDUCING FAT DEPOSITION AND TREATING ASSOCIATED CONDITIONS
(FR) METHODES THERAPEUTIQUES DE REDUCTION DU DEPOT DE GRAISSE ET TRAITEMENT DES ETATS ASSOCIES
Abstract: front page image
(EN)The invention provides methods for prognosing and diagnosing fat deposition and related disorders (e.g., obesity and non-insulin diabetes dependent mellitus (NIDDM) in a subject, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for reducing fat deposition and related disorders in a subject. These embodiments are based in part upon an analysis of polymorphic variations of nucleic acid set forth in SEQ ID NO: 1. Figure (1) depicts the PLA2G1B nucleotide sequence reported as SEQ ID NO:1.
(FR)L'invention concerne des méthodes de pronostic et de diagnostic du dépôt de graisse et des troubles associés (par exemple l'obésite et le diabète non insulino-dépendant (DNID)) chez un sujet, des réactifs, et des kits de mise en oeuvre desdites méthodes, une méthode d'identification d'agents thérapeutiques potentiels de réduction du dépôt de graisse et des troubles associés, et des méthodes thérapeutiques de réduction du dépôt de graisse ou de traitement des troubles associés au dépôt de graisse chez un sujet. Ces modes de réalisation se basent en partie sur une analyse des variations polymorphiques de l'acide nucléique de la SEQ ID NO: 1.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)