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Machine translation
1. (WO2003078393) FLUORINATED PHENYL THIOPHENYL DERIVATIVES AND THEIR USE FOR IMAGING SEROTONIN TRANSPORTERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/078393    International Application No.:    PCT/US2003/007935
Publication Date: 25.09.2003 International Filing Date: 14.03.2003
Chapter 2 Demand Filed:    10.10.2003    
IPC:
A61K 51/04 (2006.01), C07C 323/32 (2006.01), C07C 323/37 (2006.01)
Applicants: KUNG, Hank, F. [US/US]; (US) (For US Only).
SHIUE, Chyng-Yann [US/US]; (US) (For US Only).
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; Center for Technology Transfer, 3160 Chestnut Street, Suite 200, Philadelphia, PA 19104 (US) (For All Designated States Except US).
OYA, Shunichi [JP/US]; (US) (For US Only).
CHOI, Seok, Rye [KR/US]; (US) (For US Only).
SHIUE, Grace, G. [US/US]; (US) (For US Only).
FANG, Ping [CN/US]; (US) (For US Only)
Inventors: KUNG, Hank, F.; (US).
SHIUE, Chyng-Yann; (US).
OYA, Shunichi; (US).
CHOI, Seok, Rye; (US).
SHIUE, Grace, G.; (US).
FANG, Ping; (US)
Agent: COVERT, John, M.; Sterne, Kessler, Goldstein & Fox P.L.L.C., Suite 600, 1100 New York Avenue, N.W., Washington, DC 20005-3934 (US)
Priority Data:
60/364,905 14.03.2002 US
Title (EN) FLUORINATED PHENYL THIOPHENYL DERIVATIVES AND THEIR USE FOR IMAGING SEROTONIN TRANSPORTERS
(FR) DERIVES FLUORES DE PHENYL THIOPHENYL ET LEUR UTILISATION DANS L'IMAGERIE DE TRANSPORTEURS DE LA SEROTONINE
Abstract: front page image
(EN)This invention relates to novel fluorinated phenyl thiphenyl (also named diarylsulfide) derivatives and their use in Positron Emission Tomagraphy (PET) imaging of Serotonin Transporters (SERTS). The present invention also provides diagnostic compositions comprising the novel compounds of the present invention, and a pharmaceutically acceptable carrier or diluent. The invention further provides a method of imaging SERTS, comprising introducing into a patient a detectable quantity of a labeled compound of the present invention, or a pharmaceutically acceptable salt, ester, amide or prodrug thereof.
(FR)L'invention concerne de nouveaux dérivés fluorés de phényl thiphényl (également appelé diarylsulfure) ainsi que leur utilisation dans l'imagerie de type tomographie par émission de positrons (PET) des transporteurs de la sérotonine (SERTS). Par ailleurs, l'invention concerne des compositions diagnostiques qui contiennent ces nouveaux composés, ainsi qu'un diluant ou un support pharmaceutiquement acceptable. De plus, l'invention concerne un procédé d'imagerie SERTS, qui consiste à introduire dans le corps du patient une quantité détectable d'un composé marqué de l'invention, ou un promédicament, un amide, un ester ou un sel pharmaceutiquement acceptable de celui-ci.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)