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Machine translation
1. (WO2003077999) COMBINATION OFA CDK INHIBITOR AND 5-FU FOR THE TREATMENT OF CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/077999    International Application No.:    PCT/GB2003/001076
Publication Date: 25.09.2003 International Filing Date: 14.03.2003
IPC:
A61K 31/4965 (2006.01), A61K 31/506 (2006.01), A61K 31/513 (2006.01), A61K 31/519 (2006.01), A61K 45/06 (2006.01)
Applicants: CYCLACEL LIMITED [GB/GB]; 12 St. James's Square London SW1Y 4RB (GB) (For All Designated States Except US).
GREEN, Simon, Richard [GB/GB]; (GB) (For US Only).
FLEMING, Ian, Neil [GB/GB]; (GB) (For US Only).
CLARKE, Rosemary, Georgina [GB/GB]; (GB) (For US Only).
McCLUE, Steven, James [GB/GB]; (GB) (For US Only)
Inventors: GREEN, Simon, Richard; (GB).
FLEMING, Ian, Neil; (GB).
CLARKE, Rosemary, Georgina; (GB).
McCLUE, Steven, James; (GB)
Agent: CLYDE-WATSON, Zoe; D Young & Co. 21 New fetter Lane London EC4A 1DA (GB)
Priority Data:
0206203.2 15.03.2002 GB
0300295.3 07.01.2003 GB
Title (EN) COMBINATION OFA CDK INHIBITOR AND 5-FU FOR THE TREATMENT OF CANCER
(FR) ASSOCIATION D'UN INHIBITEUR DES KINASES DEPENDANTES DES CYCLINES (CDK) ET DE 5-FU DESTINEE AU TRAITEMENT DU CANCER
Abstract: front page image
(EN)A first aspect of the invention relates to a combination comprising a CDK inhibitor and 5-FU, or a prodrug thereof. A second aspect of the invention relates to a pharmaceutical product comprising a CDK inhibitor and 5-FU, or a prodrug thereof, as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method of treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering a CDK inhibitor and 5-FU, or a prodrug thereof, to a subject.
(FR)Un premier aspect de l'invention concerne une association comprenant un inhibiteur des kinases dépendantes des cyclines (CDK) et du 5-FU ou un promédicament de ce dernier. Un deuxième aspect de l'invention concerne un produit pharmaceutique comprenant un inhibiteur des kinases dépendantes des cyclines (CDK) et du 5-FU ou un promédicament de ce dernier, sous forme de préparation combinée pouvant être utilisée de façon simultanée, séquentielle ou séparée dans une thérapie. Un troisième aspect de l'invention concerne une méthode servant au traitement d'un trouble prolifératif, consistant à administrer de façon simultanée, séquentielle ou séparée, un inhibiteur des kinases dépendantes des cyclines (CDK) et du 5-FU ou un promédicament de ce dernier, à un patient.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)