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Pub. No.:    WO/2003/077945    International Application No.:    PCT/GB2003/001077
Publication Date: 25.09.2003 International Filing Date: 14.03.2003
Chapter 2 Demand Filed:    16.09.2003    
C07K 16/32 (2006.01)
Applicants: MEDICAL RESEARCH COUNCIL [GB/GB]; 20 Park Crescent, London W1B 1AL (GB) (For All Designated States Except US).
LOBATO-CABALLERO, Maria, Natividad [ES/GB]; (GB) (For US Only).
RABBITTS, Terence, Howard [GB/GB]; (GB) (For US Only)
Inventors: LOBATO-CABALLERO, Maria, Natividad; (GB).
RABBITTS, Terence, Howard; (GB)
Agent: MASCHIO, Antonio; D Young & Co., 21 New Fetter Lane, London EC4A 1DA (GB)
Priority Data:
0206043.2 14.03.2002 GB
0226723.5 15.11.2002 GB
0226727.6 15.11.2002 GB
Abstract: front page image
(EN)The present invention relates to immunoglobulin molecules which are capable of binding to a specific antigen within an intracellular environment. In particular, the invention relates to the use of intracellularly binding antibodies in the intracellular relocation and/or degradation of target ligand.
(FR)La présente invention concerne des molécules d'immunoglobuline qui sont capables de se lier à un antigène spécifique dans les limites d'un environnement intracellulaire. L'invention concerne plus particulièrement l'utilisation d'anticorps à liaison intracellulaire pour le déplacement et/ou la dégradation d'un ligand cible.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)