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1. (WO2003077870) NEW STRAINS OF MYCOPLASMA HYORHINIS AS CAUSATIVE AGENTS FOR AUTOIMMUNE DISEASE

Pub. No.:    WO/2003/077870    International Application No.:    PCT/US2003/008020
Publication Date: Fri Sep 26 01:59:59 CEST 2003 International Filing Date: Tue Mar 18 00:59:59 CET 2003
IPC: C07K 14/30
C12Q 1/68
G01N 33/564
G01N 33/569
Applicants: UNIVERSITY OF MASSACHUSSETS
DOXSEY, Stephen, J.
Inventors: DOXSEY, Stephen, J.
Title: NEW STRAINS OF MYCOPLASMA HYORHINIS AS CAUSATIVE AGENTS FOR AUTOIMMUNE DISEASE
Abstract:
The invention is based on the discovery that Mycoplasma hyorhinis (e.g., designated ATCC # PTA-3681) underlies the pathology of scleroderma and other autoimmune diseases. The invention encompasses Mycoplasma hyorhinis nucleic acid and polypeptides, methods of treating scleroderma and other autoimmune diseases by treating the underlying mycoplasma infection, compositions useful in treating scleroderma and other autoimmune diseases, methods of producing model organisms infected by mycoplasma, and a novel isolated strain of Mycoplasma hyorhinis designated ATCC # PTA-3681.