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1. (WO2003076640) A PROCESS FOR THE PREPARATION OF CEPHALOSPORAN ACID DERIVATIVES FROM CEPHALOSPORIN C
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/076640    International Application No.:    PCT/EP2003/002621
Publication Date: 18.09.2003 International Filing Date: 10.03.2003
Chapter 2 Demand Filed:    10.10.2003    
IPC:
C12P 35/02 (2006.01), C12P 35/06 (2006.01), C12P 39/00 (2006.01), C12N 9/08 (2006.01), C12N 9/80 (2006.01), C12N 9/06 (2006.01), C12N 11/02 (2006.01), C12N 11/18 (2006.01), C07D 501/20 (2006.01), C07D 501/04 (2006.01)
Applicants: BIOFERMA MURCIA, S.A. [ES/ES]; Pol. Ind. Las Salinas, Avda. de Europa, s/n, 30840 Alhama de Murcia (Murcia) (ES) (For All Designated States Except US).
GUISAN SEIJAS, Jose M. [ES/ES]; (ES) (For US Only).
FERNANDEZ LAFUENTE, Roberto [ES/ES]; (ES) (For US Only).
FERNANDEZ LORENTE, Gloria [ES/ES]; (ES) (For US Only).
BETANCORT, Lorena Dutrenit [UY/ES]; (ES) (For US Only).
HUERTAS HIDALGO, Aurelio [ES/ES]; (ES) (For US Only).
GONZÁLEZ MATEO, César [ES/ES]; (ES) (For US Only)
Inventors: GUISAN SEIJAS, Jose M.; (ES).
FERNANDEZ LAFUENTE, Roberto; (ES).
FERNANDEZ LORENTE, Gloria; (ES).
BETANCORT, Lorena Dutrenit; (ES).
HUERTAS HIDALGO, Aurelio; (ES).
GONZÁLEZ MATEO, César; (ES)
Agent: DAVILA BAZ, Ángel; c/o CLARKE, MODET & CO., c/ Goya, 11, 28001 Madrid (ES)
Priority Data:
02075989.0 12.03.2002 EP
Title (EN) A PROCESS FOR THE PREPARATION OF CEPHALOSPORAN ACID DERIVATIVES FROM CEPHALOSPORIN C
(FR) PROCEDE POUR LA PREPARATION DE DERIVES ACIDES DE CEPHALOSPORAN A PARTIR DE CEPHALOSPORINE C
Abstract: front page image
(EN)A process for the preparation of cephalosporin acid derivatives comprises the step of enzymatically converting cephalosporin C into 7 cephalosporin acid derivatives in the presence of two biocatalysts, wherein one biocatalyst comprises co-immobilised D-amino acid oxidase and a catalase enzyme, and the other biocatalyst comprises immobilised glutaryl acylase.
(FR)L'invention concerne un procédé de préparation de dérivés acides de céphalosporine comprenant l'étape de conversion enzymatique de céphalosporine C en dérivés acides de céphalosporine 7 en présence de deux biocatalyseurs, un biocatalyseur comprenant une D-aminoacide-oxydase co-immobilisée et une enzyme catalase, et l'autre biocatalyseur comprenant une glutaryl-acylase immobilisée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)