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1. (WO2003075943) BOTANICAL EXTRACT COMPOSITIONS WITH ANTI-CANCER OR PHYTOESTROGENIC ACTIVITY COMPRISING WOGONIN, ISOLIQUIRITIGENIN AND/OR COUMESTROL
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/075943    International Application No.:    PCT/US2003/006979
Publication Date: 18.09.2003 International Filing Date: 06.03.2003
IPC:
A61K 31/122 (2006.01), A61K 31/352 (2006.01), A61K 31/37 (2006.01), A61K 45/06 (2006.01)
Applicants: THE MEDICAL RESEARCH AND EDUCATION TRUST [US/US]; 1901 First Avenue, Suite 210, San Diego, CA 92101 (US)
Inventors: CHEN, Sophie, PH.D; (US)
Agent: CANTOR, Michael, A.; Cantor Colburn LLP, 55 Griffin Road South, Bloomfield, CT 06002 (US)
Priority Data:
60/362,420 06.03.2002 US
60/374,417 22.04.2002 US
Title (EN) BOTANICAL EXTRACT COMPOSITIONS WITH ANTI-CANCER OR PHYTOESTROGENIC ACTIVITY COMPRISING WOGONIN, ISOLIQUIRITIGENIN AND/OR COUMESTROL
(FR) COMPOSITIONS D'EXTRAIT BOTANIQUE ET PROCEDES D'UTILISATION
Abstract: front page image
(EN)A composition having phytoestrogenic and anti-cancer activity is described. The composition comprises wogonin, isoliquiritigenin, coumestrol, their pharmaceutically acceptable salts or esters, their selectively substituted analogs, or combinations thereof. The compositions may also include an anti-cancer agent and/or an immune stimulant. A method for treating or preventing cancer or an estrogen related disorder includes administering a therapeutically effective amount of the compositions is described. The compositions are particularly useful in the treatment of hormone-related cancers.
(FR)L'invention concerne une composition possédant une activité phyto-oestrogène et anticancéreuse. Cette composition contient de la wogonine, de l'isoliquiritigénine, du coumestrol, leurs sels ou esters acceptables sur le plan pharmaceutique, leurs analogues sélectivement substitués, ou des combinaisons de ceux-ci. Ces compositions peuvent également comprendre un agent anticancéreux ou un stimulant immun. L'invention concerne également un procédé de traitement ou de prévention du cancer ou d'un trouble lié aux oestrogènes consistant à administrer une quantité efficace sur le plan thérapeutique des compositions de l'invention. Ces compositions sont notamment utiles dans le traitement de cancers liés aux hormones.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)