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1. (WO2003074739) AUTOMATED ALLELE DETERMINATION USING FLUOROMETRIC GENOTYPING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/074739    International Application No.:    PCT/US2003/006309
Publication Date: 12.09.2003 International Filing Date: 03.03.2003
IPC:
C12Q 1/68 (2006.01), G01N 33/48 (2006.01), G01N 33/50 (2006.01), G06F 19/00 (2006.01)
Applicants: APPLERA CORPORATION [US/US]; 850 Lincoln Center Drive, Foster City, CA 94404 (US)
Inventors: GLANOWSKI, Stephen; (US).
HEIL, Jeremy; (US).
WINN-DEEN, Emily, S.; (US).
MCMULLEN, Ivy, A.; (US)
Agent: DELANEY, Karoline, A.; Knobbe, Martens, Olson & Bear, LLP, 2040 Main Street, 14th Floor, Irvine, CA 92614 (US)
Priority Data:
10/085,142 01.03.2002 US
Title (EN) AUTOMATED ALLELE DETERMINATION USING FLUOROMETRIC GENOTYPING
(FR) DETERMINATION AUTOMATISEE D'ALLELES PAR GENOTYPAGE FLUOROMETRIQUE
Abstract: front page image
(EN)The present teachings describe systems and methods for automated identification of allelic variants using amplification data. In particular, automated allelic discrimination may accomplished by analysis and comparison of sample intensities associated with fluorophore labeled nucleotide probes incorporated into amplified polymorphic DNA. These methods are useful in that they provide rapid and efficient means to distinguish polymorphic DNA sites without control samples.
(FR)L'invention concerne des systèmes et procédés d'identification automatisée de variants alléliques au moyen de données d'amplification. En particulier, on peut réaliser la discrimination allélique automatisée par analyse et comparaison d'intensités échantillons associées à des sondes nucléotidiques marquées par un fluorophore incorporées dans un ADN polymorphe amplifié. L'utilité de ces procédés réside dans le fait qu'ils fournissent des moyens rapides et efficaces pour distinguer des sites d'ADN polymorphes sans échantillons témoins.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)