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1. (WO2003074722) MICROARRAYS OF CELLULOSE BINDING CHIMERIC PROTEINS AND METHODS OF USE THEREOF

Pub. No.:    WO/2003/074722    International Application No.:    PCT/IL2003/000177
Publication Date: Sep 12, 2003 International Filing Date: Mar 6, 2003
IPC: G01N 33/543
Applicants: ZEPHYR PROTEOMIX LTD.
MORAG, Ely
Inventors: MORAG, Ely
Title: MICROARRAYS OF CELLULOSE BINDING CHIMERIC PROTEINS AND METHODS OF USE THEREOF
Abstract:
The present invention provides microarrays of proteins comprising a cellulose binding region as a means for binding to a cellulase substrate such as cellulose. The cellulose binding region may further contain biologically active exogenous moieties introduced therein while maintaining the ability to bind cellulase substrates with high affinity. In addition, methods of construction of the microarrays and using said microarrays are disclosed. The microarrays of the invention are particularly useful for displaying peptide libraries, random or rationally designed, and for high throughput screening for ligands, epitopes or ligand binding sites.