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1. (WO2003074693) DNA NANOCAGE BY SELF-ORGANIZATION OF DNA AND PROCESS FOR PRODUCING THE SAME, AND DNA NANOTUBE AND MOLECULE CARRIER USING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/074693    International Application No.:    PCT/JP2003/002644
Publication Date: 12.09.2003 International Filing Date: 06.03.2003
IPC:
A61K 9/51 (2006.01), C12N 15/10 (2006.01)
Applicants: KYUSHU TLO COMPANY, LIMITED [JP/JP]; 10-1, Hakozaki 6-chome, Higashi-ku, Fukuoka-shi, Fukuoka 812-0053 (JP) (For All Designated States Except US).
MATSUURA, Kazunori [JP/JP]; (JP) (For US Only).
KIMIZUKA, Nobuo [JP/JP]; (JP) (For US Only).
YAMASHITA, Taro [JP/JP]; (JP) (For US Only)
Inventors: MATSUURA, Kazunori; (JP).
KIMIZUKA, Nobuo; (JP).
YAMASHITA, Taro; (JP)
Agent: NAEMURA, Shinichi; Toko Bldg. 5F, 5-36, Kinko-cho, Kanagawa-ku, Yokohama-shi, Kanagawa 221-0056 (JP)
Priority Data:
2002-061504 07.03.2002 JP
Title (EN) DNA NANOCAGE BY SELF-ORGANIZATION OF DNA AND PROCESS FOR PRODUCING THE SAME, AND DNA NANOTUBE AND MOLECULE CARRIER USING THE SAME
(FR) NANOCAGE D'ADN OBTENUE PAR AUTO-ORGANISATION D'ADN ET SON PROCEDE DE PRODUCTION, ET NANOTUBE D'ADN ET SUPPORT MOLECULAIRE UTILISANT CE DERNIER
Abstract: front page image
(EN)It is intended to provide a process for producing a DNA nanocage characterized by having the step of two-dimensionally assembling three types of oligonucleotides by hybridization to thereby form a double-stranded DNA branched in three directions which has self-complementary strands at the end, and the step of self-organizing the double-stranded DNA branched in three directions thus obtained in such a manner that the self-complementary end is completely consumed three-dimensionally. The DNA nanocage can be conveniently constructed via a single stage from DNA and can hold nanoparticles enclosed therein. Owing to these characteristics, the DNA nanocage highly contributes to the development of functional materials with the use of DNA.
(FR)L'invention concerne un procédé de production d'une nanocage d'ADN. Ce procédé se caractérise en ce qu'il consiste à assembler de manière bidimensionnelle trois types d'oligonucléotides par hybridation de manière à former un ADN à double brin ramifié dans trois directions comportant des brins auto-complémentaires en extrémité, et à auto-organiser l'ADN à double brin ramifié dans trois directions ainsi obtenu de façon que l'extrémité auto-complémentaire soit complètement consommée de manière tridimensionnelle. Cette nanocage d'ADN peut être facilement construite au moyen d'une étape unique à partir d'un ADN, et peut retenir les nanoparticules qui y sont enfermées. Grâce à ces caractéristiques, ladite nanocage d'ADN contribue dans une large mesure au développement de matières fonctionnelles au moyen de l'ADN.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)