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Machine translation
1. (WO2003074028) PROCESS FOR LOADING AND THERMODYNAMICALLY ACTIVATING DRUGS ON POLYMERS BY MEANS OF SUPERCRITICAL FLUIDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/074028    International Application No.:    PCT/EP2003/002204
Publication Date: 12.09.2003 International Filing Date: 07.03.2003
Chapter 2 Demand Filed:    29.07.2003    
IPC:
A61K 9/14 (2006.01), A61K 9/16 (2006.01)
Applicants: EURAND PHARMACEUTICALS LTD. [IE/IE]; Harcourt Centre, Harcourt Street, Dublin 2 (IE) (For All Designated States Except US).
BRESCIANI, Massimo [IT/IT]; (IT) (For US Only).
DOBETTI, Luca [IT/IT]; (IT) (For US Only).
KIRCHMAYER, Stefano [IT/IT]; (IT) (For US Only)
Inventors: BRESCIANI, Massimo; (IT).
DOBETTI, Luca; (IT).
KIRCHMAYER, Stefano; (IT)
Agent: GERVASI, Gemma; Notarbartolo & Gervasi S.p.A., Corso di Porta Vittoria, 9, I-20122 Milan (IT)
Priority Data:
2002/0184 07.03.2002 IE
Title (EN) PROCESS FOR LOADING AND THERMODYNAMICALLY ACTIVATING DRUGS ON POLYMERS BY MEANS OF SUPERCRITICAL FLUIDS
(FR) PROCEDE DE CHARGEMENT ET D'ACTIVATION THERMODYNAMIQUE DE MEDICAMENTS SUR DES POLYMERES AU MOYEN DE FLUIDES SURCRITIQUES
Abstract: front page image
(EN)The present invention refers to a process of loading drugs in a thermodynamic activated form into polymers by means of supercritical fluids. The process includes a pre-treatment step of the cross-linked polymer with pure supercritical fluid to allow a higher degree and a more rapid kinetic of drug loading into cross-linked polymers and also a higher thermodynamic activation of the drugs.
(FR)La présente invention concerne un procédé de chargement de médicaments sous une forme activée thermodynamique, dans des polymères au moyen de fluides surcritiques. Ce procédé comprend une étape de pré-traitement du polymère réticulé avec un fluide surcritique pur de manière à obtenir un degré plus élevé et une cinétique plus rapide du chargement de médicaments dans des polymères réticulés et, également, une activation thermodynamique plus élevée des médicaments.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)