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Machine translation
1. (WO2003072556) GLUTAMINYL BASED DPIV INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/072556    International Application No.:    PCT/EP2002/007124
Publication Date: 04.09.2003 International Filing Date: 27.06.2002
Chapter 2 Demand Filed:    18.09.2003    
IPC:
A61K 38/04 (2006.01), A61K 38/06 (2006.01), A61K 38/07 (2006.01), A61K 38/08 (2006.01), C07D 207/04 (2006.01), C07D 277/04 (2006.01), C07K 5/083 (2006.01), C07K 5/087 (2006.01), C07K 7/06 (2006.01)
Applicants: PROSIDION LTD. [GB/GB]; Watlington Road, Oxford OX4 6LT (GB) (For All Designated States Except US).
DEMUTH, Hans-Ulrich [DE/DE]; (DE) (For US Only).
HOFFMANN, Torsten [DE/DE]; (DE) (For US Only).
HEISER, Ulrich [DE/DE]; (DE) (For US Only)
Inventors: DEMUTH, Hans-Ulrich; (DE).
HOFFMANN, Torsten; (DE).
HEISER, Ulrich; (DE)
Agent: BLAKEY, Alison; Prosidion Ltd., Watlington Road, Oxford OX4 6LT (GB)
Priority Data:
60/360,909 28.02.2002 US
Title (EN) GLUTAMINYL BASED DPIV INHIBITORS
(FR) INHIBITEURS DE DPIV A BASE DE GROUPES GLUTAMINYL
Abstract: front page image
(EN)The present invention provides a compound of the formula (I): wherein X = CH¿2? or S or a pharmaceutically acceptable salt thereof. Such compounds and their corresponding pharmaceutically acceptable acid addition salt forms, are useful in treating conditions mediated by DPIV or DPIV-like enzymes, such as arthritis, obesity, immune and autoimmune disorders, allograft transplantation, cancer, neuronal disorders and dermal diseases.
(FR)La présente invention concerne des composés de formule (I), dans laquelle X = CH2 ou S, ou un sel pharmaceutiquement acceptable de ces composés. Lesdits composés et leurs sels d'addition d'acide pharmaceutiquement acceptables correspondants sont utiles pour traiter des maladies ou des états médiés par des enzymes DPIV ou de type DPIV, tels que l'arthrite, l'obésité, les maladies immunes et auto-immunes, les allogreffes, le cancer, les troubles du système nerveux et les maladies de la peau.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)