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1. (WO2003072538) METHOD FOR PRODUCING 2-CHLOROMETHYLPHENYL ACETIC ACID DERIVATIVES

Pub. No.:    WO/2003/072538    International Application No.:    PCT/EP2003/001160
Publication Date: Sep 4, 2003 International Filing Date: Feb 6, 2003
IPC: C07C 251/38
Applicants: BASF Aktiengesellschaft
MAYER, Guido
CULLMANN, Oliver
WOLF, Bernd
KEIL, Michael
Inventors: MAYER, Guido
CULLMANN, Oliver
WOLF, Bernd
KEIL, Michael
Title: METHOD FOR PRODUCING 2-CHLOROMETHYLPHENYL ACETIC ACID DERIVATIVES
Abstract:
The invention relates to a method for producing 2-chloromethylphenyl acetic acid derivatives of formula (I), in which X represents C1-C4 alkoxy or methylamino, by cleaving the ether bonds in compounds of formula (II), in which R represents C1-C4 alkyl, C1-C4 alkoxy, C1-C2 alkyl halide, C1-C4 alkylcarbonyl, C1-C4 alkylcarbonyloxy, halogen, nitro or cyano, and X has the above-mentioned meaning. The inventive method is characterized in that the transformation takes place in the presence of hydrogen chloride and of an inert solvent, and in that a catalyst selected from the group comprised of: iron, indium or halogenides, oxides or triflates thereof is added to the reaction mixture.