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Machine translation
1. (WO2003072099) PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/072099    International Application No.:    PCT/US2003/003112
Publication Date: 04.09.2003 International Filing Date: 07.02.2003
IPC:
C07D 235/02 (2006.01), C07D 235/16 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center Indianapolis, IN 46285 (US) (For All Designated States Except US).
GIBSON, Tracey, Ann [US/US]; (US) (For US Only).
MANTLO, Nathan, Bryan [US/US]; (US) (For US Only).
THOMPSON, Richard, Craig [US/US]; (US) (For US Only)
Inventors: GIBSON, Tracey, Ann; (US).
MANTLO, Nathan, Bryan; (US).
THOMPSON, Richard, Craig; (US)
Agent: VORNDRAN-JONES, MaCharri; Eli Lilly And Company P. O. Box 6288 Indianapolis, IN 46206-6288 (US)
Priority Data:
60/359,428 21.02.2002 US
Title (EN) PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS
(FR) MODULATEURS DU RECEPTEUR ACTIVE PAR L'AGENT DE PROLIFERATION DU PEROXISOME
Abstract: front page image
(EN)The present invention is directed to compounds represented by the following structural formula, and pharmaceutically acceptable salts thereof, Formula I: and pharmaceutically acceptable salts thereof, wherein: (a) W is selected from the group consisting of O, C, N and S; (b) Z is an aliphatic linker wherein one carbon atom of the aliphatic linker may be replaced with O, NH or S, and wherein such aliphatic linker is optionally substituted with Z'; (c) A is selected from the group consisting of carboxyl, carboxamide, sulfonamide, acylsulfonamide, tetrazole, and (CH2)n COOR19, and wherein said sulfonamide, acylsulfonamide, and tetrazole is each optionally substituted with from one to three substituents each independently selected from A'.
(FR)La présente invention concerne des composés représentés par la formule structurale suivante, et des sels de ceux-ci acceptables du point de vue pharmaceutique. Dans la formule (I): (a) W est choisi dans le groupe comprenant O, C, N et S; (b) Z est un agent de liaison aliphatique, un atome de carbone de l'agent de liaison aliphatique pouvant être remplacé par O, NH ou S, et l'agent de liaison aliphatique étant éventuellement substitué avec Z'; (c) A est choisi dans le groupe comprenant carboxyle, carboxamide, sulfonamide, acylsulfonamide, tétrazole, et (CH2)n COOR19, chacun desdits sulfonamide, acylsulfonamide et tétrazole étant éventuellement substitué avec un à trois substituants choisis indépendamment dans le groupe A'.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)