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1. (WO2003071872) NOVEL TREATMENT OF NEURODEGENERATIVE DISEASES BY ALTERING LEVELS OF TRKB ISOFORMS AND/OR TRKC ISOFORMS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/071872    International Application No.:    PCT/US2002/016807
Publication Date: 04.09.2003 International Filing Date: 28.05.2002
IPC:
A61K 31/70 (2006.01)
Applicants: UNIVERSITY OF MARYLAND, BALTIMORE [US/US]; TEC COM / ORD, 520 West Lombard Street, Baltimore, MD 21201 (US) (For All Designated States Except US).
KRUEGER, Bruce, K. [US/US]; (US).
KINGSBURY, Tami, J. [US/US]; (US).
BAMBRICK, Linda, L. [US/US]; (US).
DORSEY, Susan, G. [US/US]; (US)
Inventors: KRUEGER, Bruce, K.; (US).
KINGSBURY, Tami, J.; (US).
BAMBRICK, Linda, L.; (US).
DORSEY, Susan, G.; (US)
Agent: MARKS, David, L.; University of Maryland, Baltimore, Office of Research and Development, 515 West Lombard Street, 5th Floor, Baltimore, MD 21201 (US)
Priority Data:
PCT/US02/05151 22.02.2002 US
Title (EN) NOVEL TREATMENT OF NEURODEGENERATIVE DISEASES BY ALTERING LEVELS OF TRKB ISOFORMS AND/OR TRKC ISOFORMS
(FR) NOUVEAU TRAITEMENT DE MALADIES NEURODEGENERATIVES PAR MODIFICATION DE NIVEAUX D'ISOFORMES TRKB ET/OU TRKC
Abstract: front page image
(EN)This invention relates to a method of treating or preventing neuro-degenerative disorders and neuro-developmental disorders by altering the ratio of the amount of full-length TrkB polypeptide to the amount of truncated TrkB polypeptides in a neuron or by altering the ratio of the amount of full-length TrkC polypeptide to the amount of truncated TrkC polypeptides in a neuron.
(FR)L'invention concerne un procédé de traitement ou de prévention de troubles neurodégénératifs et de troubles neurodéveloppementaux par modification du rapport de la quantité de polypeptides TrkB pleine longueur à la quantité de polypeptides TrkB tronqués dans un neurone ou par modification du rapport de la quantité de polypeptides TrkC pleine longueur à la quantité de polypeptides TrkC tronqués dans un neurone.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)